You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Whole genome HBV deletion profiles and the accumulation of preS deletion mutant during antiviral treatment
|
|---|---|
| Published in |
BMC Microbiology, December 2012
|
| DOI | 10.1186/1471-2180-12-307 |
| Pubmed ID | |
| Authors |
Dake Zhang, Peiling Dong, Ke Zhang, Libin Deng, Christian Bach, Wei Chen, Feifei Li, Ulrike Protzer, Huiguo Ding, Changqing Zeng |
| Abstract |
Hepatitis B virus (HBV), because of its error-prone viral polymerase, has a high mutation rate leading to widespread substitutions, deletions, and insertions in the HBV genome. Deletions may significantly change viral biological features complicating the progression of liver diseases. However, the clinical conditions correlating to the accumulation of deleted mutants remain unclear. In this study, we explored HBV deletion patterns and their association with disease status and antiviral treatment by performing whole genome sequencing on samples from 51 hepatitis B patients and by monitoring changes in deletion variants during treatment. Clone sequencing was used to analyze preS regions in another cohort of 52 patients. |
X Demographics
The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 25% |
| Turkey | 1 | 13% |
| Colombia | 1 | 13% |
| Unknown | 4 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 8 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 4% |
| Canada | 1 | 2% |
| Unknown | 52 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 15 | 27% |
| Researcher | 10 | 18% |
| Student > Master | 8 | 15% |
| Student > Doctoral Student | 2 | 4% |
| Other | 2 | 4% |
| Other | 6 | 11% |
| Unknown | 12 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 12 | 22% |
| Agricultural and Biological Sciences | 10 | 18% |
| Biochemistry, Genetics and Molecular Biology | 9 | 16% |
| Immunology and Microbiology | 3 | 5% |
| Nursing and Health Professions | 1 | 2% |
| Other | 6 | 11% |
| Unknown | 14 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 January 2013.
All research outputs
#6,229,476
of 23,301,510 outputs
Outputs from BMC Microbiology
#674
of 3,238 outputs
Outputs of similar age
#65,544
of 283,103 outputs
Outputs of similar age from BMC Microbiology
#30
of 97 outputs
Altmetric has tracked 23,301,510 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 3,238 research outputs from this source. They receive a mean Attention Score of 4.2. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 283,103 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 97 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.