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CHAGASIC MENINGOENCEPHALITIS IN AN HIV INFECTED PATIENT WITH MODERATE IMMUNOSUPPRESSION: PROLONGED SURVIVAL AND CHALLENGES IN THE HAART ERA

Overview of attention for article published in Revista do Instituto de Medicina Tropical de São Paulo, December 2015
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Title
CHAGASIC MENINGOENCEPHALITIS IN AN HIV INFECTED PATIENT WITH MODERATE IMMUNOSUPPRESSION: PROLONGED SURVIVAL AND CHALLENGES IN THE HAART ERA
Published in
Revista do Instituto de Medicina Tropical de São Paulo, December 2015
DOI 10.1590/s0036-46652015000600014
Pubmed ID
Authors

Renata BUCCHERI, Maria José KASSAB, Vera Lucia Teixeira de FREITAS, Sheila Cristina Vicente da SILVA, Rita C. BEZERRA, Zarifa KHOURY, Maria Aparecida SHIKANAI-YASUDA, José E. VIDAL

Abstract

The reactivation of Chagas disease in HIV infected patients presents high mortality and morbidity. We present the case of a female patient with confirmed Chagasic meningoencephalitis as AIDS-defining illness. Interestingly, her TCD4+ lymphocyte cell count was 318 cells/mm3. After two months of induction therapy, one year of maintenance with benznidazol, and early introduction of highly active antiretroviral therapy (HAART), the patient had good clinical, parasitological and radiological evolution. We used a qualitative polymerase chain reaction for the monitoring of T. cruzi parasitemia during and after the treatment. We emphasize the potential value of molecular techniques along with clinical and radiological parameters in the follow-up of patients with Chagas disease and HIV infection. Early introduction of HAART, prolonged induction and maintenance of antiparasitic therapy, and its discontinuation are feasible, in the current management of reactivation of Chagas disease.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 1 7%
Unknown 14 93%
Readers by discipline Count As %
Medicine and Dentistry 1 7%
Unknown 14 93%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 September 2016.
All research outputs
#11,171,782
of 12,556,257 outputs
Outputs from Revista do Instituto de Medicina Tropical de São Paulo
#251
of 251 outputs
Outputs of similar age
#219,237
of 261,391 outputs
Outputs of similar age from Revista do Instituto de Medicina Tropical de São Paulo
#1
of 1 outputs
Altmetric has tracked 12,556,257 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 251 research outputs from this source. They receive a mean Attention Score of 2.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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