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Twice-weekly aripiprazole for treating children and adolescents with tic disorder, a randomized controlled clinical trial

Overview of attention for article published in Annals of General Psychiatry, August 2016
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Title
Twice-weekly aripiprazole for treating children and adolescents with tic disorder, a randomized controlled clinical trial
Published in
Annals of General Psychiatry, August 2016
DOI 10.1186/s12991-016-0112-4
Pubmed ID
Authors

Ahmad Ghanizadeh

Abstract

Treating tic disorder is challenging. No trial has ever examined whether twice weekly aripiprazole is effective for treating tic disorders. Participants of this 8-week randomized controlled parallel-group clinical trial were a clinical sample of 36 children and adolescents with tic disorder. Yale global tic severity scale was used to assess the outcome. Both groups received daily dosage of aripiprazole for the first 14 days. Then, one group received daily dose of aripiprazole while the other group received twice weekly dosage of aripiprazole for the next 46 days. The patients were assessed at baseline, week 2, 4, and 8. Tic scores decreased in both group significantly 22.8 (18.5) versus 22.0 (11.6). Moreover, there was no between group difference. The final mean (SD) score of motor and vocal tics in the group treated with daily treatment was not significantly different from the twice weekly group (Cohen's d = 0.36). The odds ratios for sedation and increased appetite were 3.05 and 3, respectively. For the first time, current findings support that twice weekly aripiprazole efficacy was not different from that of daily treatment. The rate of drowsiness in the twice weekly treatment group was less than that of the daily treatment group. This trial was registered at http://www.irct.ir. The registration number of this trial was: IRCT201312263930N32. http://www.irct.ir/searchresult.php?id=3930&number=32.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 38 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 9 24%
Student > Master 5 13%
Researcher 4 11%
Student > Ph. D. Student 4 11%
Other 3 8%
Other 2 5%
Unknown 11 29%
Readers by discipline Count As %
Medicine and Dentistry 9 24%
Psychology 8 21%
Nursing and Health Professions 7 18%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Neuroscience 1 3%
Other 0 0%
Unknown 12 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 September 2016.
All research outputs
#14,860,134
of 22,886,568 outputs
Outputs from Annals of General Psychiatry
#267
of 511 outputs
Outputs of similar age
#205,085
of 336,871 outputs
Outputs of similar age from Annals of General Psychiatry
#6
of 9 outputs
Altmetric has tracked 22,886,568 research outputs across all sources so far. This one is in the 33rd percentile – i.e., 33% of other outputs scored the same or lower than it.
So far Altmetric has tracked 511 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 336,871 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.