Title |
EnRICH: Extraction and Ranking using Integration and Criteria Heuristics
|
---|---|
Published in |
BMC Systems Biology, January 2013
|
DOI | 10.1186/1752-0509-7-4 |
Pubmed ID | |
Authors |
Xia Zhang, M Heather West Greenlee, Jeanne M Serb |
Abstract |
High throughput screening technologies enable biologists to generate candidate genes at a rate that, due to time and cost constraints, cannot be studied by experimental approaches in the laboratory. Thus, it has become increasingly important to prioritize candidate genes for experiments. To accomplish this, researchers need to apply selection requirements based on their knowledge, which necessitates qualitative integration of heterogeneous data sources and filtration using multiple criteria. A similar approach can also be applied to putative candidate gene relationships. While automation can assist in this routine and imperative procedure, flexibility of data sources and criteria must not be sacrificed. A tool that can optimize the trade-off between automation and flexibility to simultaneously filter and qualitatively integrate data is needed to prioritize candidate genes and generate composite networks from heterogeneous data sources. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | 4% |
Unknown | 23 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 5 | 21% |
Student > Doctoral Student | 3 | 13% |
Student > Bachelor | 3 | 13% |
Professor | 3 | 13% |
Student > Ph. D. Student | 2 | 8% |
Other | 6 | 25% |
Unknown | 2 | 8% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 8 | 33% |
Biochemistry, Genetics and Molecular Biology | 4 | 17% |
Medicine and Dentistry | 3 | 13% |
Engineering | 3 | 13% |
Computer Science | 2 | 8% |
Other | 2 | 8% |
Unknown | 2 | 8% |