Quality of mutations does matter (and failure of TMB to predict benefit from ICI in NSCLC is a demonstration). Non-sense mRNA decay may impact on quality of mutation, tumor antigenicity and response to ICI. @dandanix76 @MarioPaoloColo1 @JournalofExper1 ht
RT @JournalofExper1: New! 💥 Deciphering the 𝐧𝐨𝐧𝐬𝐞𝐧𝐬𝐞-𝐦𝐞𝐝𝐢𝐚𝐭𝐞𝐝 𝐦𝐑𝐍𝐀 𝐝𝐞𝐜𝐚𝐲 𝐩𝐚𝐭𝐡𝐰𝐚𝐲 to identify cancer cell vulnerabilities for effective can…
Deciphering the 𝐧𝐨𝐧𝐬𝐞𝐧𝐬𝐞-𝐦𝐞𝐝𝐢𝐚𝐭𝐞𝐝 𝐦𝐑𝐍𝐀 𝐝𝐞𝐜𝐚𝐲 𝐩𝐚𝐭𝐡𝐰𝐚𝐲 to identify cancer cell vulnerabilities for effective cancer therapy
New! 💥 Deciphering the 𝐧𝐨𝐧𝐬𝐞𝐧𝐬𝐞-𝐦𝐞𝐝𝐢𝐚𝐭𝐞𝐝 𝐦𝐑𝐍𝐀 𝐝𝐞𝐜𝐚𝐲 𝐩𝐚𝐭𝐡𝐰𝐚𝐲 to identify cancer cell vulnerabilities for effective cancer therapy Full text ⏬ https://t.co/0qqbyPgHG8 #ImmuneCheckpointInhibitor #NonsenseMediatedmRNAdecay @IREISGufficiale https://t.co/oIg