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Coinfection with influenza A(H1N1)pdm09 and dengue virus in fatal cases

Overview of attention for article published in Memórias do Instituto Oswaldo Cruz, September 2016
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (67th percentile)
  • Good Attention Score compared to outputs of the same age and source (72nd percentile)

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1 policy source
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1 Facebook page

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Title
Coinfection with influenza A(H1N1)pdm09 and dengue virus in fatal cases
Published in
Memórias do Instituto Oswaldo Cruz, September 2016
DOI 10.1590/0074-02760160140
Pubmed ID
Authors

Anne Carolinne Bezerra Perdigão, Izabel Letícia Cavalcante Ramalho, Maria Izabel Florindo Guedes, Deborah Nunes Melo Braga, Luciano Pamplona Góes Cavalcanti, Maria Elisabeth Lisboa de Melo, Rafael Montenegro de Carvalho Araújo, Elza Gadelha Lima, Luciene Alexandre Bié da Silva, Lia de Carvalho Araújo, Fernanda Montenegro de Carvalho Araújo

Abstract

We report on four patients with fatal influenza A(H1N1)pdm09 and dengue virus coinfections. Clinical, necropsy and histopathologic findings presented in all cases were characteristic of influenza-dengue coinfections, and all were laboratory-confirmed for both infections. The possibility of influenza and dengue coinfection should be considered in locations where these two viruses' epidemic periods coincide to avoid fatal outcomes. Dengue is a mosquito-borne viral infection caused by one of the four dengue viruses (DENV-1 to 4). Each of these viruses is capable of causing nonspecific febrile illnesses, classic dengue fever and dengue haemorrhagic fever (Gubler 1998). As a result, dengue is often difficult to diagnose clinically, especially because peak dengue season often coincides with that of other common febrile illnesses in tropical regions (Chacon et al. 2015). In April 2009, a new virus, influenza A/H1N1/pandemic (FluA/H1N1/09pdm), caused a severe outbreak in Mexico. The virus quickly spread throughout the world, and in June 2009, the World Health Organization declared a pandemic (WHO 2010). In Brazil, the first laboratory confirmed case of FluA/H1N1/09pdm was in July 2009 (Pires Neto et al. 2013). The state of Ceará, in Northeast Brazil, is a dengue endemic area. In this state, the virus influenza A(H1N1)pdm09 has circulated since 2009, and through the first half of 2012, 11 deaths caused by the virus were confirmed (Pires Neto et al. 2013). The influenza and dengue seasons in Ceará overlap, which led to diagnostic difficulties. We report four cases of laboratory-confirmed coinfection of deadly influenza A(H1N1)pdm09 with DENV, which occurred during the dengue and influenza season in 2012 and 2013 in Ceará.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 2%
Unknown 41 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 19%
Student > Bachelor 7 17%
Researcher 6 14%
Student > Ph. D. Student 4 10%
Student > Postgraduate 3 7%
Other 6 14%
Unknown 8 19%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 9 21%
Medicine and Dentistry 6 14%
Immunology and Microbiology 3 7%
Agricultural and Biological Sciences 3 7%
Veterinary Science and Veterinary Medicine 2 5%
Other 8 19%
Unknown 11 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 January 2018.
All research outputs
#7,777,586
of 25,371,288 outputs
Outputs from Memórias do Instituto Oswaldo Cruz
#276
of 1,502 outputs
Outputs of similar age
#112,642
of 348,359 outputs
Outputs of similar age from Memórias do Instituto Oswaldo Cruz
#5
of 18 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 1,502 research outputs from this source. They receive a mean Attention Score of 4.6. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 348,359 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.