You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Sex, stress, and epigenetics: regulation of behavior in animal models of mood disorders
|
|---|---|
| Published in |
Biology of Sex Differences, January 2013
|
| DOI | 10.1186/2042-6410-4-1 |
| Pubmed ID | |
| Authors |
Georgia E Hodes |
| Abstract |
Women have a higher incidence of stress related disorders including depression and generalized anxiety disorder, and epigenetic mechanisms likely contribute to this sex difference. Evidence from preclinical research suggests that epigenetic mechanisms are responsible for both sexual dimorphism of brain regions and sensitivity of the stress response. Epigenetic modifications such as DNA methylation and histone modifications can occur transgenerationally, developmentally, or in response to environmental stimuli such as stress exposure. This review will provide an overview of the various forms of epigenetic modifications observed in the central nervous system and will explain how these mechanisms contribute to a sexually dimorphic brain. It will also discuss the ways in which epigenetic alterations coincide with, and functionally contribute to, the behavioral response to stress across the lifespan. Ultimately, this review will focus on novel research utilizing animal models to investigate sex differences in epigenetic mechanisms that influence susceptibility to stress. Exploration of this relationship reveals epigenetic mechanisms with the potential to explain sexual dimorphism in the occurrence of stress related disorders. |
X Demographics
The data shown below were collected from the profiles of 18 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 9 | 50% |
| United Kingdom | 1 | 6% |
| Mexico | 1 | 6% |
| Unknown | 7 | 39% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 9 | 50% |
| Scientists | 6 | 33% |
| Science communicators (journalists, bloggers, editors) | 2 | 11% |
| Practitioners (doctors, other healthcare professionals) | 1 | 6% |
Mendeley readers
The data shown below were compiled from readership statistics for 105 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 2% |
| Argentina | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 101 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 19 | 18% |
| Student > Bachelor | 16 | 15% |
| Student > Master | 15 | 14% |
| Researcher | 10 | 10% |
| Student > Postgraduate | 5 | 5% |
| Other | 18 | 17% |
| Unknown | 22 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 21 | 20% |
| Agricultural and Biological Sciences | 19 | 18% |
| Medicine and Dentistry | 15 | 14% |
| Psychology | 13 | 12% |
| Biochemistry, Genetics and Molecular Biology | 6 | 6% |
| Other | 8 | 8% |
| Unknown | 23 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 April 2023.
All research outputs
#3,575,426
of 25,654,806 outputs
Outputs from Biology of Sex Differences
#149
of 592 outputs
Outputs of similar age
#35,207
of 288,637 outputs
Outputs of similar age from Biology of Sex Differences
#4
of 8 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 592 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.9. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 288,637 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.