↓ Skip to main content

Stem Cell Heterogeneity

Overview of attention for book
Cover of 'Stem Cell Heterogeneity'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 315 Isolation and Culture of Embryonic Stem Cells, Mesenchymal Stem Cells, and Dendritic Cells from Humans and Mice
  3. Altmetric Badge
    Chapter 319 Maintenance of Dermal Papilla Cells by Wnt-10b In Vitro
  4. Altmetric Badge
    Chapter 320 Maintenance of Skin Epithelial Stem Cells by Wnt-3a In Vitro
  5. Altmetric Badge
    Chapter 321 Isolation and Expansion of Muscle Precursor Cells from Human Skeletal Muscle Biopsies
  6. Altmetric Badge
    Chapter 322 An Effective and Reliable Xeno-free Cryopreservation Protocol for Single Human Pluripotent Stem Cells
  7. Altmetric Badge
    Chapter 323 Induction of a Tumor-Metastasis-Receptive Microenvironment as an Unwanted Side Effect After Radio/Chemotherapy and In Vitro and In Vivo Assays to Study this Phenomenon
  8. Altmetric Badge
    Chapter 324 Decoding the Epigenetic Heterogeneity of Human Pluripotent Stem Cells with Seamless Gene Editing
  9. Altmetric Badge
    Chapter 325 Stencil Micropatterning for Spatial Control of Human Pluripotent Stem Cell Fate Heterogeneity
  10. Altmetric Badge
    Chapter 326 Isolation and Characterization of Cancer Stem Cells of the Non-Small-Cell Lung Cancer (A549) Cell Line
  11. Altmetric Badge
    Chapter 327 Aerosol-Based Cell Therapy for Treatment of Lung Diseases
  12. Altmetric Badge
    Chapter 327 Erratum to: Enzyme-Free Dissociation of Neurospheres by a Microfluidic Chip-Based Method
  13. Altmetric Badge
    Chapter 328 Induction of Inner Ear Hair Cells from Mouse Embryonic Stem Cells In Vitro
  14. Altmetric Badge
    Chapter 329 In Vitro Culture of Human Hematopoietic Stem Cells in Serum Free Medium and Their Monitoring by Flow Cytometry
  15. Altmetric Badge
    Chapter 342 Isolation and Propagation of Glioma Stem Cells from Acutely Resected Tumors
  16. Altmetric Badge
    Chapter 343 Clonal Analysis of Cells with Cellular Barcoding: When Numbers and Sizes Matter
  17. Altmetric Badge
    Chapter 344 Automated Cell-Based Quantitation of 8-OHdG Damage
  18. Altmetric Badge
    Chapter 345 Heterogeneity of Stem Cells: A Brief Overview
  19. Altmetric Badge
    Chapter 346 Agent-Based Modeling of Cancer Stem Cell Driven Solid Tumor Growth.
  20. Altmetric Badge
    Chapter 347 Establishment and Characterization of Naïve Pluripotency in Human Embryonic Stem Cells.
  21. Altmetric Badge
    Chapter 348 Enzyme-Free Dissociation of Neurospheres by a Microfluidic Chip-Based Method
  22. Altmetric Badge
    Chapter 349 Visualizing the Functional Heterogeneity of Muscle Stem Cells
  23. Altmetric Badge
    Chapter 350 CoCl2 Administration to Vascular MSC Cultures as an In Vitro Hypoxic System to Study Stem Cell Survival and Angiogenesis
  24. Altmetric Badge
    Chapter 356 Dissecting Transcriptional Heterogeneity in Pluripotency: Single Cell Analysis of Mouse Embryonic Stem Cells
  25. Altmetric Badge
    Chapter 357 Generation of Regionally Specific Neural Progenitor Cells (NPCs) and Neurons from Human Pluripotent Stem Cells (hPSCs)
  26. Altmetric Badge
    Chapter 358 Measuring ATP Concentration in a Small Number of Murine Hematopoietic Stem Cells.
  27. Altmetric Badge
    Chapter 360 Reporter Systems to Study Cancer Stem Cells
  28. Altmetric Badge
    Chapter 361 Analysis of Cell Cycle Status of Murine Hematopoietic Stem Cells
  29. Altmetric Badge
    Chapter 362 Growth Factor-Free Pre-vascularization of Cell Sheets for Tissue Engineering
Attention for Chapter 323: Induction of a Tumor-Metastasis-Receptive Microenvironment as an Unwanted Side Effect After Radio/Chemotherapy and In Vitro and In Vivo Assays to Study this Phenomenon
Altmetric Badge

Citations

dimensions_citation
2 Dimensions

Readers on

mendeley
4 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Chapter title
Induction of a Tumor-Metastasis-Receptive Microenvironment as an Unwanted Side Effect After Radio/Chemotherapy and In Vitro and In Vivo Assays to Study this Phenomenon
Chapter number 323
Book title
Stem Cell Heterogeneity
Published in
Methods in molecular biology, April 2016
DOI 10.1007/7651_2016_323
Pubmed ID
Book ISBNs
978-1-4939-6549-6, 978-1-4939-6550-2
Authors

Gabriela Schneider, Zachariah Payne Sellers, Mariusz Z. Ratajczak, Schneider, Gabriela, Sellers, Zachariah Payne, Ratajczak, Mariusz Z.

Abstract

Besides surgical removal of tumor tissue, chemotherapy and radiotherapy are the most important and efficient treatment modalities employed to treat therapy-susceptible malignancies. The main aim of this treatment-to destroy tumor cells-is unfortunately usually associated with toxicity to nontumor cells and different degrees of tissue and organ damage. In damaged tissues several chemoattractants are upregulated and released that may attract tumor cells. Moreover, highly migratory radio/chemotherapy treatment may endow cells with several properties of cancer stem cells which survive and respond to these chemoattractants upregulated in collateral tissues. Based on this, one of the unwanted and underappreciated side effects of chemotherapy or radiotherapy is the creation of a metastasis-receptive microenvironment in bones as well as in other organs of the body. Herein we describe methods and assays that can be employed to study migratory properties of cancer cells in in vitro (chemotaxis) and in vivo (seeding efficiency assay) conditions in response to the induction of pro-metastatic microenvironments in various organs and tissues.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 4 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 4 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 1 25%
Student > Bachelor 1 25%
Unknown 2 50%
Readers by discipline Count As %
Medicine and Dentistry 2 50%
Unknown 2 50%