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DNA-guided genome editing using structure-guided endonucleases

Overview of attention for article published in Genome Biology, September 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (84th percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

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8 X users
patent
6 patents

Citations

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10 Dimensions

Readers on

mendeley
72 Mendeley
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Title
DNA-guided genome editing using structure-guided endonucleases
Published in
Genome Biology, September 2016
DOI 10.1186/s13059-016-1055-4
Pubmed ID
Authors

Gaurav K. Varshney, Shawn M. Burgess

Abstract

The search for novel ways to target and alter the genomes of living organisms accelerated rapidly this decade with the discovery of CRISPR/Cas9. Since the initial discovery, efforts to find alternative methods for altering the genome have expanded. A new study presenting an alternative approach has been demonstrated that utilizes flap endonuclease 1 (FEN-1) fused to the Fok1 endonuclease, which shows potential for DNA-guided genome targeting in vivo.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 1%
Unknown 71 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 17 24%
Student > Master 12 17%
Student > Ph. D. Student 10 14%
Other 8 11%
Student > Doctoral Student 7 10%
Other 8 11%
Unknown 10 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 23 32%
Biochemistry, Genetics and Molecular Biology 22 31%
Immunology and Microbiology 5 7%
Medicine and Dentistry 4 6%
Chemistry 2 3%
Other 5 7%
Unknown 11 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 February 2024.
All research outputs
#3,307,781
of 25,374,917 outputs
Outputs from Genome Biology
#2,377
of 4,467 outputs
Outputs of similar age
#52,642
of 329,608 outputs
Outputs of similar age from Genome Biology
#35
of 54 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,608 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 54 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.