D1R can signal through multiple downstream pathways and specific signaling may differ between cell types or be altered in disease. D1R drug development has potential utility of D1R-agonists in Parkinson's Disease and cognitive impairment. #Multispan #GPCR
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RT @FrontNeurosci: New Research: The Signaling and Pharmacology of the Dopamine D1 Receptor: The dopamine D1 receptor (D1R) is a Gαs/olf-co…
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New Research: The Signaling and Pharmacology of the Dopamine D1 Receptor: The dopamine D1 receptor (D1R) is a Gαs/olf-coupled GPCR that is expressed in the midbrain and forebrain, regulating motor behavior, reward, motivational states, and… https://t.co/eD
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RT @THebertMcGill: We just published a review on D1 dopamine receptor signalling. Great work by @jace_jt, Hanan Mohammad and Emma Paulus. A…