بعض الطفرات في جين مستقبل الإستروجين ESR1 تزيد من قدرة الخلايا السرطانية على الهجرة وتشكيل النقائل ولكنها تجعل الورم أكثر استجابة للعلاج المناعي https://t.co/Xrl9d8e30m
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Hotspot ESR1 Mutations Are Multimodal and Contextual Modulators of Breast Cancer Metastasis | Cancer Research | American Association for Cancer Research https://t.co/2M8kvjyg9S
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BREAST: activating ESR1 mutations are known to confer resistance to endocrine therapy; new preclinical/translational studies implicate ESR1 mutation in driving metastatic spread. https://t.co/QPnpFnS399
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RRIDs were included in the Cancer Research paper "Hotspot ESR1 mutations are multimodal and contextu…" (https://t.co/E5BI1JsPMw). RRIDs like this improve reproducibility in scientific research. #ReproducibleResearch #reproducibility