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Obesity

Overview of attention for book
Obesity
Elsevier Science
Attention for Chapter: Ghrelin at the interface of obesity and reward.
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  • Average Attention Score compared to outputs of the same age
  • Above-average Attention Score compared to outputs of the same age and source (54th percentile)

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3 X users

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75 Mendeley
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Chapter title
Ghrelin at the interface of obesity and reward.
Book title
Obesity
Published in
Vitamins & Hormones, January 2013
DOI 10.1016/b978-0-12-407766-9.00013-4
Pubmed ID
Book ISBNs
978-0-12-407766-9
Authors

Harriët Schellekens, Timothy G. Dinan, John F. Cryan

Abstract

The prevalence of obesity continues to increase and has reached epidemic proportions. Accumulating data over the past few decades have given us key insights and broadened our understanding of the peripheral and central regulation of energy homeostasis. Despite this, the currently available pharmacological treatments, reducing body weight, remain limited due to poor efficacy and side effects. The gastric peptide ghrelin has been identified as the only orexigenic hormone from the periphery to act in the hypothalamus to stimulate food intake. Recently, a role for ghrelin and its receptor at the interface between homeostatic control of appetite and reward circuitries modulating the hedonic aspects of food has also emerged. Nonhomeostatic factors such as the rewarding and motivational value of food, which increase with food palatability and caloric content, can override homeostatic control of food intake. This nonhomeostatic decision to eat leads to overconsumption beyond nutritional needs and is being recognized as a key component in the underlying causes for the increase in obesity incidence worldwide. In addition, the hedonic feeding behavior has been linked to food addiction and an important role for ghrelin in the development of addiction has been suggested. Moreover, plasma ghrelin levels are responsive to conditions of stress, and recent evidence has implicated ghrelin in stress-induced food-reward behavior. The prominent role of the ghrelinergic system in the regulation of feeding gives rise to it as an effective target for the development of successful antiobesity pharmacotherapies that not only affect satiety but also selectively modulate the rewarding properties of food and reduce the desire to eat.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Kazakhstan 1 1%
Poland 1 1%
Ireland 1 1%
Australia 1 1%
Unknown 71 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 24%
Researcher 9 12%
Student > Master 6 8%
Student > Postgraduate 5 7%
Student > Bachelor 5 7%
Other 15 20%
Unknown 17 23%
Readers by discipline Count As %
Agricultural and Biological Sciences 16 21%
Medicine and Dentistry 12 16%
Neuroscience 8 11%
Psychology 5 7%
Social Sciences 3 4%
Other 12 16%
Unknown 19 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 February 2013.
All research outputs
#13,680,290
of 22,694,633 outputs
Outputs from Vitamins & Hormones
#204
of 437 outputs
Outputs of similar age
#161,915
of 280,671 outputs
Outputs of similar age from Vitamins & Hormones
#5
of 11 outputs
Altmetric has tracked 22,694,633 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 437 research outputs from this source. They receive a mean Attention Score of 4.4. This one has gotten more attention than average, scoring higher than 53% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,671 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.