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Capillary Electrophoresis

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Cover of 'Capillary Electrophoresis'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 1 The CE-Way of Thinking: "All Is Relative!".
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    Chapter 2 A Semiempirical Approach for a Rapid Comprehensive Evaluation of the Electrophoretic Behaviors of Small Molecules in Free Zone Electrophoresis.
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    Chapter 3 Derivatization in Capillary Electrophoresis.
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    Chapter 4 Statically Adsorbed Coatings for High Separation Efficiency and Resolution in CE-MS Peptide Analysis: Strategies and Implementation.
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    Chapter 5 Micellar Electrokinetic Chromatography of Aminoglycosides.
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    Chapter 6 Microemulsion Electrokinetic Chromatography.
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    Chapter 7 Nonaqueous Capillary Electrophoresis Mass Spectrometry.
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    Chapter 8 Ionic Liquids in Capillary Electrophoresis.
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    Chapter 9 CZE-CZE ESI-MS Coupling with a Fully Isolated Mechanical Valve.
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    Chapter 10 Capillary Electrophoresis-Inductively Coupled Plasma Mass Spectrometry.
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    Chapter 11 Use of CE to Analyze Solutes in Pico- and Nano-Liter Samples from Plant Cells and Rhizosphere.
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    Chapter 12 Analysis of Small Ions with Capillary Electrophoresis.
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    Chapter 13 Metal Ions Analysis with Capillary Zone Electrophoresis.
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    Chapter 14 Bioanalytical Application of Amino Acid Detection by Capillary Electrophoresis.
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    Chapter 15 Enantiomer Separations by Capillary Electrophoresis.
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    Chapter 16 Capillary Electrophoresis of Mono- and Oligosaccharides.
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    Chapter 17 Use of Capillary Electrophoresis for Polysaccharide Studies and Applications.
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    Chapter 18 Separation of Peptides by Capillary Electrophoresis.
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    Chapter 19 Microbial Analysis of Escherichia coli ATCC, Lactobacteria and Saccharomyces cerevisiae Using Capillary Electrophoresis Approach.
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    Chapter 20 Capillary Electrophoretic Analysis of Classical Organic Pollutants.
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    Chapter 21 Capillary Electrophoresis in Metabolomics.
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    Chapter 22 Capillary Electrophoresis in Food and Foodomics.
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    Chapter 23 Capillary Electrophoresis in Wine Science.
Attention for Chapter 9: CZE-CZE ESI-MS Coupling with a Fully Isolated Mechanical Valve.
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Chapter title
CZE-CZE ESI-MS Coupling with a Fully Isolated Mechanical Valve.
Chapter number 9
Book title
Capillary Electrophoresis
Published in
Methods in molecular biology, January 2016
DOI 10.1007/978-1-4939-6403-1_9
Pubmed ID
Book ISBNs
978-1-4939-6401-7, 978-1-4939-6403-1
Authors

Felix J. Kohl, Christian Neusüß

Editors

Philippe Schmitt-Kopplin

Abstract

The hyphenation of capillary electrophoresis and electrospray ionization-mass spectrometry is a powerful tool for peptide and protein analysis. It provides high separation power in combination with sensitive and selective detection and the possibility of analyte identification. Unfortunately, many proven capillary electrophoresis methods are not compatible with electrospray-mass spectrometry since several compounds of best separating background electrolytes are interfering in the electrospray ionization. Here, we describe a two-dimensional capillary electrophoresis system using the second dimension as a cleanup stage in order to remove interfering compounds to enable electrospray-mass spectrometry coupling.

Mendeley readers

The data shown below were compiled from readership statistics for 1 Mendeley reader of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 1 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 1 100%
Readers by discipline Count As %
Chemistry 1 100%