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Taurine 8

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Cover of 'Taurine 8'

Table of Contents

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    Book Overview
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    Chapter 1 Neuropsychopharmacological Actions of Taurine
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    Chapter 2 Taurine and Its Neuroprotective Role
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    Chapter 3 Antidepressant-Like Effect of Chronic Taurine Administration and Its Hippocampal Signal Transduction in Rats
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    Chapter 4 Direct Interaction of Taurine with the NMDA Glutamate Receptor Subtype via Multiple Mechanisms
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    Chapter 5 The modulatory role of taurine in retinal ganglion cells.
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    Chapter 6 Taurine is a crucial factor to preserve retinal ganglion cell survival.
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    Chapter 7 Taurine regulation of voltage-gated channels in retinal neurons.
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    Chapter 8 The Effect of Folic Acid on GABA(A)-B 1 Receptor Subunit.
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    Chapter 9 Taurine counteracts the suppressive effect of lipopolysaccharide on neurogenesis in the hippocampus of rats.
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    Chapter 10 Perinatal taurine exposure programs patterns of autonomic nerve activity responses to tooth pulp stimulation in adult male rats.
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    Chapter 11 Regulation of Taurine Release in the Hippocampus of Developing and Adult Mice
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    Chapter 12 Evaluation of the taurine concentrations in dog plasma and aqueous humour: a pilot study.
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    Chapter 13 Protective effect of taurine on down-regulated expression of thyroid hormone receptor genes in brains of mice exposed to arsenic.
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    Chapter 14 Taurine exerts robust protection against hypoxia and oxygen/glucose deprivation in human neuroblastoma cell culture.
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    Chapter 15 The effects of chronic taurine supplementation on motor learning.
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    Chapter 16 Changes in gene expression at inhibitory synapses in response to taurine treatment.
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    Chapter 17 Taurine Effects on Emotional Learning and Memory in Aged Mice: Neurochemical Alterations and Differentiation in Auditory Cued Fear and Context Conditioning
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    Chapter 18 Rising taurine and ethanol concentrations in nucleus accumbens interact to produce the dopamine-activating effects of alcohol.
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    Chapter 19 Thiotaurine prevents apoptosis of human neutrophils: a putative role in inflammation.
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    Chapter 20 Protection by Taurine Against INOS-Dependent DNA Damage in Heavily Exercised Skeletal Muscle by Inhibition of the NF-κB Signaling Pathway.
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    Chapter 21 Effect of taurine chloramine on differentiation of human preadipocytes into adipocytes.
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    Chapter 22 Taurine Chloramine Administered In Vivo Increases NRF2-Regulated Antioxidant Enzyme Expression in Murine Peritoneal Macrophages.
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    Chapter 23 Influence of Taurine Haloamines (TauCl and TauBr) on the Development of Pseudomonas aeruginosa Biofilm: A Preliminary Study.
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    Chapter 24 Inhibitory Effects of Taurine on STZ-Induced Apoptosis of Pancreatic Islet Cells.
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    Chapter 25 Taurine's Effects on the Neuroendocrine Functions of Pancreatic β Cells.
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    Chapter 26 Antidiabetic effect of taurine in cultured rat skeletal l6 myotubes.
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    Chapter 27 Protection by taurine and thiotaurine against biochemical and cellular alterations induced by diabetes in a rat model.
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    Chapter 28 The effects of taurine and thiotaurine on oxidative stress in the aorta and heart of diabetic rats.
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    Chapter 29 Comparative evaluation of taurine and thiotaurine as protectants against diabetes-induced nephropathy in a rat model.
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    Chapter 30 Taurine may not alleviate hyperglycemia-mediated endoplasmic reticulum stress in human adipocytes.
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    Chapter 31 Taurine regulation of blood pressure and vasoactivity.
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    Chapter 32 Synergistic effects of taurine and L-arginine on attenuating insulin resistance hypertension.
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    Chapter 33 High Sugar Intake Blunts Arterial Baroreflex via Estrogen Receptors in Perinatal Taurine Supplemented Rats.
Attention for Chapter 31: Taurine regulation of blood pressure and vasoactivity.
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (61st percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

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1 Wikipedia page

Citations

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Readers on

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13 Mendeley
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Chapter title
Taurine regulation of blood pressure and vasoactivity.
Chapter number 31
Book title
Taurine 8
Published in
Advances in experimental medicine and biology, January 2013
DOI 10.1007/978-1-4614-6130-2_31
Pubmed ID
Book ISBNs
978-1-4614-6129-6, 978-1-4614-6130-2
Authors

Idrissi AE, Okeke E, Yan X, Sidime F, Neuwirth LS, Abdeslem El Idrissi, Evelyn Okeke, Xin Yan, Francoise Sidime, Lorenz S. Neuwirth, Idrissi, Abdeslem El, Okeke, Evelyn, Yan, Xin, Sidime, Francoise, Neuwirth, Lorenz S.

Editors

Abdeslem El Idrissi, William J. L'Amoreaux

Abstract

Taurine plays an important role in the modulation of cardiovascular function by acting not only within the brain but also within peripheral tissues. We found that IV injection of taurine to male rats caused hypotension and tachycardia. A single injection of taurine significantly lowered the systolic, diastolic, and mean arterial blood pressure in freely moving Long-Evans control rats. We further confirm the vasoactive properties of taurine using isolated aortic ring preparations. Mechanical responses of circular aortic rings to pharmacological agents were measured by an isometric force transducer and amplifier. We found that bath application of taurine to the aortic rings caused vasodilation which was blocked by picrotoxin. Interestingly, picrotoxin alone induced a constriction of the aortic ring in the absence of exogenously added taurine, suggesting a tonic activation of GABA(A)receptors by circulating either taurine or GABA. Additionally, we found that the endothelial cells express high levels of taurine transporters and GABA(A)receptors. We have previously shown that taurine activates GABA(A)receptors and thus we suggest that the functional implication of GABA(A)receptor activation is the relaxation of the arterial muscularis, vasodilation, and a decrease in blood pressure. Interestingly however, the effects of acute taurine injection were very different than chronic supplementation of taurine. When rats were supplemented taurine (0.05%, 4 weeks) in their drinking water, taurine has significant hypertensive properties. The increase in blood pressure was observed however only in females; males supplemented with taurine did not show an increase in systolic, diastolic, or mean arterial pressure. In both genders however, taurine supplementation caused a significant tachycardia. Thus, we suggest that acute administration of taurine may be beneficial to lowering blood pressure. However, our data indicate that supplementation of taurine to females caused a significant increase in blood pressure. The effect of taurine supplementation on hypertensive rats remains to be seen.

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 13 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 31%
Researcher 3 23%
Student > Doctoral Student 2 15%
Student > Master 1 8%
Professor 1 8%
Other 0 0%
Unknown 2 15%
Readers by discipline Count As %
Neuroscience 3 23%
Biochemistry, Genetics and Molecular Biology 2 15%
Agricultural and Biological Sciences 2 15%
Nursing and Health Professions 2 15%
Social Sciences 1 8%
Other 2 15%
Unknown 1 8%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 August 2014.
All research outputs
#4,047,566
of 13,536,508 outputs
Outputs from Advances in experimental medicine and biology
#615
of 3,272 outputs
Outputs of similar age
#45,313
of 152,143 outputs
Outputs of similar age from Advances in experimental medicine and biology
#6
of 12 outputs
Altmetric has tracked 13,536,508 research outputs across all sources so far. This one is in the 49th percentile – i.e., 49% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,272 research outputs from this source. They receive a mean Attention Score of 3.6. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 152,143 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.