Melanoma cells produce amyloid beta (AB), a peptide central to Alzheimer's disease. Melanoma-secreted AB protects brain metastasis against immune destruction by astrocytes and microglia. Treatment of mice with an anti-AB therapy originally designed for Alzheimer's disease decreased brain metastasis. User postalkwk, in the Neuroscience: News and Discussions. subreddit, 10 Mar 2022