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Angiotensin-I Converting Enzyme (ACE) Inhibitory and Anti-Hypertensive Effect of Protein Hydrolysate from Actinopyga lecanora (Sea Cucumber) in Rats

Overview of attention for article published in Marine Drugs, September 2016
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1 tweeter

Citations

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20 Dimensions

Readers on

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55 Mendeley
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Title
Angiotensin-I Converting Enzyme (ACE) Inhibitory and Anti-Hypertensive Effect of Protein Hydrolysate from Actinopyga lecanora (Sea Cucumber) in Rats
Published in
Marine Drugs, September 2016
DOI 10.3390/md14100176
Pubmed ID
27706040
Authors

Mahdokht Sadegh Vishkaei, Afshin Ebrahimpour, Azizah Abdul-Hamid, Amin Ismail, Nazamid Saari

Abstract

Food protein hydrolysates are known to exhibit angiotensin converting enzyme (ACE) inhibitory properties and can be used as a novel functional food for prevention of hypertension. This study evaluated the ACE inhibitory potentials of Actinopyga lecanora proteolysate (ALP) in vivo. The pre-fed rats with ALP at various doses (200, 400, 800 mg/kg body weight) exhibited a significant (p ≤ 0.05) suppression effect after inducing hypertension. To determine the optimum effective dose that will produce maximal reduction in blood pressure, ALP at three doses was fed to the rats after inducing hypertension. The results showed that the 800 mg/kg body weight dose significantly reduced blood pressure without noticeable negative physiological effect. In addition, there were no observable changes in the rats' heart rate after oral administration of the ALP. It was concluded that Actinopyga lecanora proteolysate could potentially be used for the development of functional foods and nutraceuticals for prevention and treatment of hypertension.

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Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 55 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 20%
Student > Bachelor 8 15%
Student > Ph. D. Student 7 13%
Student > Doctoral Student 4 7%
Unspecified 4 7%
Other 8 15%
Unknown 13 24%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 8 15%
Unspecified 4 7%
Agricultural and Biological Sciences 4 7%
Medicine and Dentistry 4 7%
Chemistry 4 7%
Other 14 25%
Unknown 17 31%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 October 2016.
All research outputs
#18,473,108
of 22,890,496 outputs
Outputs from Marine Drugs
#2,528
of 3,561 outputs
Outputs of similar age
#244,709
of 322,482 outputs
Outputs of similar age from Marine Drugs
#43
of 57 outputs
Altmetric has tracked 22,890,496 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,561 research outputs from this source. They receive a mean Attention Score of 4.5. This one is in the 9th percentile – i.e., 9% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 322,482 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 57 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.

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