Title |
Cerebrovascular pattern improved by ozone autohemotherapy: an entropy-based study on multiple sclerosis patients
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Published in |
Medical & Biological Engineering & Computing, October 2016
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DOI | 10.1007/s11517-016-1580-z |
Pubmed ID | |
Authors |
Filippo Molinari, Daniele Rimini, William Liboni, U. Rajendra Acharya, Marianno Franzini, Sergio Pandolfi, Giovanni Ricevuti, Francesco Vaiano, Luigi Valdenassi, Vincenzo Simonetti |
Abstract |
Ozone major autohemotherapy is effective in reducing the symptoms of multiple sclerosis (MS) patients, but its effects on brain are still not clear. In this work, we have monitored the changes in the cerebrovascular pattern of MS patients and normal subjects during major ozone autohemotherapy by using near-infrared spectroscopy (NIRS) as functional and vascular technique. NIRS signals are analyzed using a combination of time, time-frequency analysis and nonlinear analysis of intrinsic mode function signals obtained from empirical mode decomposition technique. Our results show that there is an improvement in the cerebrovascular pattern of all subjects indicated by increasing the entropy of the NIRS signals. Hence, we can conclude that the ozone therapy increases the brain metabolism and helps to recover from the lower activity levels which is predominant in MS patients. |
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Unknown | 3 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 44 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 11 | 25% |
Other | 4 | 9% |
Professor > Associate Professor | 4 | 9% |
Student > Postgraduate | 3 | 7% |
Student > Ph. D. Student | 3 | 7% |
Other | 6 | 14% |
Unknown | 13 | 30% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 11 | 25% |
Nursing and Health Professions | 4 | 9% |
Agricultural and Biological Sciences | 3 | 7% |
Neuroscience | 3 | 7% |
Engineering | 3 | 7% |
Other | 5 | 11% |
Unknown | 15 | 34% |