Title |
Chromatin structural changes around satellite repeats on the female sex chromosome in Schistosoma mansoni and their possible role in sex chromosome emergence
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Published in |
Genome Biology, February 2012
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DOI | 10.1186/gb-2012-13-2-r14 |
Pubmed ID | |
Authors |
Julie MJ Lepesant, Céline Cosseau, Jérome Boissier, Michael Freitag, Julien Portela, Déborah Climent, Cécile Perrin, Adhemar Zerlotini, Christoph Grunau |
Abstract |
In the leuphotrochozoan parasitic platyhelminth Schistosoma mansoni, male individuals are homogametic (ZZ) whereas females are heterogametic (ZW). To elucidate the mechanisms that led to the emergence of sex chromosomes, we compared the genomic sequence and the chromatin structure of male and female individuals. As for many eukaryotes, the lower estimate for the repeat content is 40%, with an unknown proportion of domesticated repeats. We used massive sequencing to de novo assemble all repeats, and identify unambiguously Z-specific, W-specific and pseudoautosomal regions of the S. mansoni sex chromosomes. |
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Côte d'Ivoire | 1 | 10% |
Canada | 1 | 10% |
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Unknown | 3 | 30% |
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Brazil | 1 | 2% |
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Researcher | 9 | 22% |
Student > Master | 4 | 10% |
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Student > Postgraduate | 3 | 7% |
Other | 3 | 7% |
Unknown | 7 | 17% |
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Other | 0 | 0% |
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