Title |
Treatment of Lennox‐Gastaut syndrome
|
---|---|
Published in |
Cochrane database of systematic reviews, February 2013
|
DOI | 10.1002/14651858.cd003277.pub3 |
Pubmed ID | |
Authors |
Eleanor C Hancock, J Helen Cross |
Abstract |
The Lennox-Gastaut syndrome (LGS) is an age-specific disorder, characterised by epileptic seizures, a characteristic electroencephalogram (EEG), psychomotor delay and behavioural disorder. It occurs more frequently in males and onset is usually before the age of eight years, with a peak between three and five years of age. Late cases occurring in adolescence and early adulthood have rarely been reported. Language is frequently affected, with both slowness in ideation and expression in addition to difficulties of motor dysfunction. Severe behavioural disorders (e.g. hyperactivity, aggressiveness and autistic tendencies) and personality disorders are nearly always present. There is also a tendency for psychosis to develop with time. The long-term prognosis is poor; although the epilepsy often improves, complete seizure freedom is rare and conversely the mental and psychiatric disorders tend to worsen with time. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
India | 1 | <1% |
Unknown | 230 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 34 | 15% |
Researcher | 30 | 13% |
Student > Bachelor | 29 | 13% |
Student > Ph. D. Student | 27 | 12% |
Student > Doctoral Student | 20 | 9% |
Other | 36 | 16% |
Unknown | 56 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 67 | 29% |
Psychology | 28 | 12% |
Nursing and Health Professions | 15 | 6% |
Neuroscience | 15 | 6% |
Social Sciences | 7 | 3% |
Other | 29 | 13% |
Unknown | 71 | 31% |