↓ Skip to main content
What is this page? Embed badge

RNA Imaging

Overview of attention for book
Cover of 'RNA Imaging'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Imaging Functional Nucleic Acid Delivery to Skin.
  3. Altmetric Badge
    Chapter 2 In Vivo Magnetic Resonance Imaging of Small Interfering RNA Nanodelivery to Pancreatic Islets.
  4. Altmetric Badge
    Chapter 3 Magnetic Resonance Spectroscopy of siRNA-Based Cancer Therapy.
  5. Altmetric Badge
    Chapter 4 Targeted Delivery with Imaging Assessment of siRNA Expressing Nanocassettes into Cancer.
  6. Altmetric Badge
    Chapter 5 RNA Imaging
  7. Altmetric Badge
    Chapter 6 Indium-Labeling of siRNA for Small Animal SPECT Imaging.
  8. Altmetric Badge
    Chapter 7 Imaging of Electrotransferred siRNA.
  9. Altmetric Badge
    Chapter 8 Whole-Body Scanning PCR, a Tool for the Visualization of the In Vivo Biodistribution Pattern of Endogenous and Exogenous Oligonucleotides in Rodents.
  10. Altmetric Badge
    Chapter 9 siRNA Nanoparticles for Ultra-Long Gene Silencing In Vivo.
  11. Altmetric Badge
    Chapter 10 Sensing miRNA: Signal Amplification by Cognate RISC for Intracellular Detection of miRNA in Live Cells.
  12. Altmetric Badge
    Chapter 11 Molecular Beacon-Based MicroRNA Imaging During Neurogenesis.
  13. Altmetric Badge
    Chapter 12 Hypoxia-Responsive Copolymer for siRNA Delivery.
  14. Altmetric Badge
    Chapter 13 Controlling RNA Expression in Cancer Using Iron Oxide Nanoparticles Detectable by MRI and In Vivo Optical Imaging.
  15. Altmetric Badge
    Chapter 14 Microvesicles: Isolation, Characterization for In Vitro and In Vivo Procedures.
  16. Altmetric Badge
    Chapter 15 Positive Bioluminescence Imaging of MicroRNA Expression in Small Animal Models Using an Engineered Genetic-Switch Expression System, RILES.
  17. Altmetric Badge
    Chapter 16 MicroRNA Imaging in Combination with Diagnostic Ultrasound and Bubble Liposomes for MicroRNA Delivery.
Attention for Chapter 6: Indium-Labeling of siRNA for Small Animal SPECT Imaging.
Altmetric Badge

Mentioned by

twitter
1 X user

Citations

dimensions_citation
3 Dimensions

Readers on

mendeley
8 Mendeley
Summary X Dimensions citations
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Chapter title
Indium-Labeling of siRNA for Small Animal SPECT Imaging.
Chapter number 6
Book title
RNA Imaging
Published in
Methods in molecular biology, January 2016
DOI 10.1007/978-1-4939-3148-4_6
Pubmed ID
26530916
Book ISBNs
978-1-4939-3147-7, 978-1-4939-3148-4
Authors

Jones, Steven, Merkel, Olivia, Steven Jones, Olivia Merkel

Editors

Zdravka Medarova

Abstract

Ever since the discovery of RNA interference (RNAi), therapeutic delivery of siRNA has attracted a lot of interest. However, due to the nature and structure of siRNA, a carrier is needed for any mode of systemic treatment. Furthermore, specific imaging techniques are required to trace where the deposition of the siRNA occurs throughout the body after treatment. Tracking in vivo siRNA biodistribution allows understanding and interpreting therapeutics effects and side effects. A great advantage of noninvasive imaging techniques such as SPECT imaging is that several time points can be assessed in the same subject. Thus, the time course of biodistribution or metabolic processes can be followed. Therefore, we have described an approach to modify siRNA with a DTPA (Diethylene Triamine Pentaacetic Acid) chelator in order to utilize an indium labeled siRNA for SPECT imaging. Here, we explain the details of the labeling and purification procedures.

View on publisher site
X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Professor 2 25%
Researcher 2 25%
Student > Bachelor 2 25%
Student > Ph. D. Student 1 13%
Unknown 1 13%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 1 13%
Agricultural and Biological Sciences 1 13%
Psychology 1 13%
Neuroscience 1 13%
Chemistry 1 13%
Other 1 13%
Unknown 2 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 November 2015.
All research outputs
#18,430,119
of 22,832,057 outputs
Outputs from Methods in molecular biology
#7,920
of 13,126 outputs
Outputs of similar age
#284,422
of 393,555 outputs
Outputs of similar age from Methods in molecular biology
#846
of 1,470 outputs
Altmetric has tracked 22,832,057 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,126 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 393,555 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1,470 others from the same source and published within six weeks on either side of this one. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.

This page is provided by Altmetric.