Title |
Nonadherence in type 2 diabetes: practical considerations for interpreting the literature
|
---|---|
Published in |
Patient preference and adherence, March 2013
|
DOI | 10.2147/ppa.s30613 |
Pubmed ID | |
Authors |
David (Dave) Blackburn, Swidrovich, Lemstra |
Abstract |
The rising prevalence of type 2 diabetes poses a serious threat to human health and the viability of many health care systems around the world. Although several prescription medications can play a vital role in controlling symptoms and preventing complications, non-adherence to these therapies is highly prevalent and has been linked to increases in morbidity, mortality, and health care costs. Although a vast array of significant adherence predictors has been identified, the ability to explain or predict non-adherence with known risk-factors remains poor. Further, the definitions, outcomes, and various measures used in the non-adherence literature can be misleading for the unfamiliar reviewer. In this narrative review, a practical overview of important considerations for interpreting adherence endpoints and measures is discussed. Also, an organizational framework is proposed to consider published adherence interventions. This framework may allow for a unique appreciation into areas of limited knowledge and thus highlights targets for future research. |
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