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Targeting Ferroptosis Vulnerability in Synovial Sarcoma: Is It All About ME1?

Overview of attention for article published in Clinical Cancer Research, July 2022
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

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36 tweeters
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Title
Targeting Ferroptosis Vulnerability in Synovial Sarcoma: Is It All About ME1?
Published in
Clinical Cancer Research, July 2022
DOI 10.1158/1078-0432.ccr-22-1257
Pubmed ID
Authors

Vivek Subbiah, Boyi Gan

Abstract

Understanding metabolic dependencies and their therapeutic vulnerabilities are key to precision oncology. Malic enzyme1 (ME1) is frequently overexpressed in cancers with pro-tumorigenic effects. In contrast, consistent loss of ME1 expression in synovial sarcoma compared with other sarcomas indicates a unique ferroptosis liability for precision therapy in this form of cancer.

Twitter Demographics

The data shown below were collected from the profiles of 36 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Attention Score in Context

This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 July 2022.
All research outputs
#1,633,007
of 21,609,784 outputs
Outputs from Clinical Cancer Research
#1,255
of 12,292 outputs
Outputs of similar age
#24,117
of 258,361 outputs
Outputs of similar age from Clinical Cancer Research
#27
of 117 outputs
Altmetric has tracked 21,609,784 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 12,292 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.2. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 258,361 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 117 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.