Table of Contents

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   Book Overview
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   Chapter 1 Tumor staging and grading: a primer.
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   Chapter 2 Clinical trial design in the age of molecular profiling.
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   Chapter 3 Personalized medicine: ethics for clinical trials.
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   Chapter 4 Reduction of preanalytical variability in specimen procurement for molecular profiling.
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   Chapter 5 The human side of cancer biobanking.
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   Chapter 6 Introduction to genomics.
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   Chapter 7 Genomic profiling: cDNA arrays and oligoarrays.
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   Chapter 8 Genome-wide methylation profiling in archival formalin-fixed paraffin-embedded tissue samples.
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    Chapter 9 An Overview of MicroRNA Methods: Expression Profiling and Target Identification.
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    Chapter 10 Antibody Validation by Western Blotting
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    Chapter 11 Laser Capture Microdissection: Arcturus(XT) Infrared Capture and UV Cutting Methods.
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    Chapter 12 Antibody microarrays: analysis of cystic fibrosis.
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    Chapter 13 Tissue microarrays as a tool in the discovery and validation of predictive biomarkers.
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    Chapter 14 Reverse-phase protein microarrays.
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    Chapter 15 Serum low-molecular-weight protein fractionation for biomarker discovery.
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    Chapter 16 Mass spectrometry-based biomarker discovery.
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    Chapter 17 Mitochondrial proteome: toward the detection and profiling of disease associated alterations.
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    Chapter 18 Adult neural stem cells: isolation and propagation.
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    Chapter 19 Evanescent-wave field imaging: an introduction to total internal reflection fluorescence microscopy.
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    Chapter 20 Construction and hyperspectral imaging of quantum dot lysate arrays.
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    Chapter 21 Microarray data analysis: comparing two population means.
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    Chapter 22 Bioinformatics/Biostatistics: microarray analysis.
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    Chapter 23 Structure-based functional design of drugs: from target to lead compound.
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    Chapter 24 Personalized medicine: changing the paradigm of drug development.
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    Chapter 25 Grant writing tips for translational research.
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    Chapter 26 Inventions and patents: a practical tutorial.
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    Chapter 27 Regulatory approval pathways for molecular diagnostic technology.
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    Chapter 28 Small business development for molecular diagnostics.