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Long Non-Coding RNAs

Overview of attention for book
Cover of 'Long Non-Coding RNAs'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 LncRNA Pulldown Combined with Mass Spectrometry to Identify the Novel LncRNA-Associated Proteins.
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    Chapter 2 Cross-Linking Immunoprecipitation and qPCR (CLIP-qPCR) Analysis to Map Interactions Between Long Noncoding RNAs and RNA-Binding Proteins.
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    Chapter 3 Characterization of Long Noncoding RNA-Associated Proteins by RNA-Immunoprecipitation.
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    Chapter 4 Isolation of Protein Complexes Associated with Long Noncoding RNAs.
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    Chapter 5 Profiling Long Noncoding RNA Expression Using Custom-Designed Microarray.
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    Chapter 6 Long Noncoding RNA Expression Profiling Using Arraystar LncRNA Microarrays.
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    Chapter 7 Nuclear RNA Isolation and Sequencing.
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    Chapter 8 Targeted LncRNA Sequencing with the SeqCap RNA Enrichment System.
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    Chapter 9 ChIP-Seq: Library Preparation and Sequencing.
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    Chapter 10 Stellaris(®) RNA Fluorescence In Situ Hybridization for the Simultaneous Detection of Immature and Mature Long Noncoding RNAs in Adherent Cells.
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    Chapter 11 Simultaneous RNA-DNA FISH.
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    Chapter 12 Visualizing Long Noncoding RNAs on Chromatin.
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    Chapter 13 Non-isotopic Method for In Situ LncRNA Visualization and Quantitation.
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    Chapter 14 Detection of Long Noncoding RNA Expression by Nonradioactive Northern Blots.
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    Chapter 15 Assessment of In Vivo siRNA Delivery in Cancer Mouse Models.
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    Chapter 16 Targeting Long Noncoding RNA with Antisense Oligonucleotide Technology as Cancer Therapeutics.
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    Chapter 17 Characterization of Circular RNAs.
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    Chapter 18 Methods for Characterization of Alternative RNA Splicing.
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    Chapter 19 NONCODEv4: Annotation of Noncoding RNAs with Emphasis on Long Noncoding RNAs.
  21. Altmetric Badge
    Chapter 20 Computational Analysis of LncRNA from cDNA Sequences.
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    Chapter 21 Analyzing MiRNA-LncRNA Interactions.
  23. Altmetric Badge
    Chapter 22 Long Noncoding RNAs: An Overview.
Attention for Chapter 15: Assessment of In Vivo siRNA Delivery in Cancer Mouse Models.
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Chapter title
Assessment of In Vivo siRNA Delivery in Cancer Mouse Models.
Chapter number 15
Book title
Long Non-Coding RNAs
Published in
Methods in molecular biology, January 2016
DOI 10.1007/978-1-4939-3378-5_15
Pubmed ID
26721492
Book ISBNs
978-1-4939-3376-1, 978-1-4939-3378-5
Authors

Hatakeyama, Hiroto, Wu, Sherry Y, Mangala, Lingegowda S, Lopez-Berestein, Gabriel, Sood, Anil K, Hiroto Hatakeyama, Sherry Y. Wu, Lingegowda S. Mangala, Gabriel Lopez-Berestein, Anil K. Sood, Wu, Sherry Y., Mangala, Lingegowda S., Sood, Anil K.

Editors

Yi Feng, Lin Zhang

Abstract

RNA interference (RNAi) has rapidly become a powerful tool for target discovery and therapeutics. Small interfering RNAs (siRNAs) are highly effective in mediating sequence-specific gene silencing. However, the major obstacle for using siRNAs as cancer therapeutics is their systemic delivery from the administration site to target cells in vivo. This chapter describes approaches to deliver siRNA effectively for cancer treatment and discusses in detail the current methods to assess pharmacokinetics and biodistribution of siRNAs in vivo.

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X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 23 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 26%
Student > Ph. D. Student 4 17%
Other 1 4%
Student > Doctoral Student 1 4%
Professor 1 4%
Other 3 13%
Unknown 7 30%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 7 30%
Pharmacology, Toxicology and Pharmaceutical Science 2 9%
Agricultural and Biological Sciences 2 9%
Medicine and Dentistry 1 4%
Neuroscience 1 4%
Other 1 4%
Unknown 9 39%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 January 2016.
All research outputs
#18,433,196
of 22,836,570 outputs
Outputs from Methods in molecular biology
#7,921
of 13,126 outputs
Outputs of similar age
#284,426
of 393,564 outputs
Outputs of similar age from Methods in molecular biology
#846
of 1,470 outputs
Altmetric has tracked 22,836,570 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,126 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
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We're also able to compare this research output to 1,470 others from the same source and published within six weeks on either side of this one. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.

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