Chapter title |
Long Noncoding RNAs: An Overview.
|
---|---|
Chapter number | 22 |
Book title |
Long Non-Coding RNAs
|
Published in |
Methods in molecular biology, January 2016
|
DOI | 10.1007/978-1-4939-3378-5_22 |
Pubmed ID | |
Book ISBNs |
978-1-4939-3376-1, 978-1-4939-3378-5
|
Authors |
Zhang, Dongmei, Xiong, Minmin, Xu, Congjian, Xiang, Peng, Zhong, Xiaomin, Dongmei Zhang, Minmin Xiong, Congjian Xu, Peng Xiang, Xiaomin Zhong |
Editors |
Yi Feng, Lin Zhang |
Abstract |
Recently an explosion in the discovery of long noncoding RNAs (lncRNAs) was obtained by high throughput sequencing. Genome-wide transcriptome analyses, in conjugation with research for epigenetic modifications of chromatins, identified a novel type of non-protein-coding transcripts longer than 200 nucleotides named lncRNAs. They are gradually emerging as functional and critical participants in many physiological processes. Here we give an overview of the characteristics, biological functions, and working mechanism for this new class of noncoding factors. |
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