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Developmental timing and critical windows for the treatment of psychiatric disorders

Overview of attention for article published in Nature Medicine, October 2016
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

news
1 news outlet
blogs
1 blog
twitter
55 X users
patent
2 patents
facebook
1 Facebook page
f1000
1 research highlight platform

Citations

dimensions_citation
288 Dimensions

Readers on

mendeley
544 Mendeley
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Title
Developmental timing and critical windows for the treatment of psychiatric disorders
Published in
Nature Medicine, October 2016
DOI 10.1038/nm.4225
Pubmed ID
Authors

Oscar Marín

Abstract

There is a growing understanding that pathological genetic variation and environmental insults during sensitive periods in brain development have long-term consequences on brain function, which range from learning disabilities to complex psychiatric disorders such as schizophrenia. Furthermore, recent experiments in animal models suggest that therapeutic interventions during sensitive periods, typically before the onset of clear neurological and behavioral symptoms, might prevent or ameliorate the development of specific pathologies. These studies suggest that understanding the dynamic nature of the pathophysiological mechanisms underlying psychiatric disorders is crucial for the development of effective therapies. In this Perspective, I explore the emerging concept of developmental windows in psychiatric disorders, their relevance for understanding disease progression and their potential for the design of new therapies. The limitations and caveats of early interventions in psychiatric disorders are also discussed in this context.

X Demographics

X Demographics

The data shown below were collected from the profiles of 55 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 544 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
United States 1 <1%
France 1 <1%
Austria 1 <1%
Unknown 540 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 100 18%
Student > Ph. D. Student 95 17%
Student > Master 57 10%
Student > Bachelor 41 8%
Student > Doctoral Student 33 6%
Other 106 19%
Unknown 112 21%
Readers by discipline Count As %
Neuroscience 148 27%
Agricultural and Biological Sciences 76 14%
Medicine and Dentistry 45 8%
Psychology 41 8%
Biochemistry, Genetics and Molecular Biology 38 7%
Other 52 10%
Unknown 144 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 51. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 April 2023.
All research outputs
#837,361
of 25,721,020 outputs
Outputs from Nature Medicine
#2,235
of 9,406 outputs
Outputs of similar age
#15,771
of 322,058 outputs
Outputs of similar age from Nature Medicine
#47
of 82 outputs
Altmetric has tracked 25,721,020 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 9,406 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 105.7. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 322,058 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 82 others from the same source and published within six weeks on either side of this one. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.