Chapter title |
Overview of Mammary Gland Development: A Comparison of Mouse and Human.
|
---|---|
Chapter number | 1 |
Book title |
Mammary Gland Development
|
Published in |
Methods in molecular biology, January 2017
|
DOI | 10.1007/978-1-4939-6475-8_1 |
Pubmed ID | |
Book ISBNs |
978-1-4939-6473-4, 978-1-4939-6475-8
|
Authors |
Sara McNally, Torsten Stein, McNally, Sara, Stein, Torsten |
Editors |
Finian Martin, Torsten Stein, Jillian Howlin |
Abstract |
The mouse mammary gland is widely used as a model for human breast cancer and has greatly added to our understanding of the molecular mechanisms involved in breast cancer development and progression. To fully appreciate the validity and limitations of the mouse model, it is essential to be aware of the similarities and also the differences that exist between the mouse mammary gland and the human breast. This introduction therefore describes the parallels and contrasts in mouse mammary gland and human breast morphogenesis from an early embryonic phase through to puberty, adulthood, pregnancy, parturition, and lactation, and finally the regressive stage of involution. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 89 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 18 | 20% |
Student > Bachelor | 11 | 12% |
Student > Master | 11 | 12% |
Researcher | 6 | 7% |
Student > Doctoral Student | 5 | 6% |
Other | 12 | 13% |
Unknown | 26 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 25 | 28% |
Agricultural and Biological Sciences | 11 | 12% |
Pharmacology, Toxicology and Pharmaceutical Science | 8 | 9% |
Unspecified | 3 | 3% |
Medicine and Dentistry | 3 | 3% |
Other | 8 | 9% |
Unknown | 31 | 35% |