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The neuronal insulin sensitizer dicholine succinate reduces stress-induced depressive traits and memory deficit: possible role of insulin-like growth factor 2

Overview of attention for article published in BMC Neuroscience, September 2012
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (71st percentile)
  • Good Attention Score compared to outputs of the same age and source (75th percentile)

Mentioned by

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1 patent
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1 Google+ user

Citations

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57 Dimensions

Readers on

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75 Mendeley
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Title
The neuronal insulin sensitizer dicholine succinate reduces stress-induced depressive traits and memory deficit: possible role of insulin-like growth factor 2
Published in
BMC Neuroscience, September 2012
DOI 10.1186/1471-2202-13-110
Pubmed ID
Authors

Brandon H Cline, Harry WM Steinbusch, Dmitry Malin, Alexander V Revishchin, Galia V Pavlova, Raymond Cespuglio, Tatyana Strekalova

Abstract

A number of epidemiological studies have established a link between insulin resistance and the prevalence of depression. The occurrence of depression was found to precede the onset of diabetes and was hypothesized to be associated with inherited inter-related insufficiency of the peripheral and central insulin receptors. Recently, dicholine succinate, a sensitizer of the neuronal insulin receptor, was shown to stimulate insulin-dependent H2O2 production of the mitochondrial respiratory chain leading to an enhancement of insulin receptor autophosphorylation in neurons. As such, this mechanism can be a novel target for the elevation of insulin signaling.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 1 1%
Unknown 74 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 15%
Student > Ph. D. Student 11 15%
Student > Bachelor 10 13%
Researcher 7 9%
Other 6 8%
Other 11 15%
Unknown 19 25%
Readers by discipline Count As %
Psychology 11 15%
Neuroscience 11 15%
Agricultural and Biological Sciences 10 13%
Medicine and Dentistry 10 13%
Pharmacology, Toxicology and Pharmaceutical Science 5 7%
Other 6 8%
Unknown 22 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 January 2019.
All research outputs
#6,389,976
of 22,703,044 outputs
Outputs from BMC Neuroscience
#308
of 1,240 outputs
Outputs of similar age
#46,312
of 170,563 outputs
Outputs of similar age from BMC Neuroscience
#6
of 29 outputs
Altmetric has tracked 22,703,044 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 1,240 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 170,563 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.