Title |
Quality of life and related factors among chronic hepatitis B-infected patients: a multi-center study, Turkey
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Published in |
Health and Quality of Life Outcomes, November 2016
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DOI | 10.1186/s12955-016-0557-9 |
Pubmed ID | |
Authors |
Zehra Karacaer, Banu Cakir, Hakan Erdem, Kenan Ugurlu, Gul Durmus, Nevin Koc Ince, Cinar Ozturk, Rodrigo Hasbun, Ayse Batirel, Esmeray Mutlu Yilmaz, Ilkay Bozkurt, Mustafa Sunbul, Aynur Aynioglu, Aynur Atilla, Ayse Erbay, Ayse Inci, Cigdem Kader, Elif Tukenmez Tigen, Gokhan Karaahmetoglu, Seher Ayten Coskuner, Ebru Dik, Huseyin Tarakci, Selma Tosun, Fatime Korkmaz, Servet Kolgelier, Fatma Yilmaz Karadag, Serpil Erol, Kamuran Turker, Ceyda Necan, Ahmet Melih Sahin, Pinar Ergen, Gulsen Iskender, Pinar Korkmaz, Esma Gulesen Eroglu, Yasemin Durdu, Mehmet Ulug, Suna Secil Deniz, Filiz Koc, Saygın Nayman Alpat, Nefise Oztoprak, Omer Evirgen, Hamdi Sozen, Mustafa Dogan, Selcuk Kaya, Safak Kaya, Mustafa Altindis, Emel Aslan, Recep Tekin, Busra Ergut Sezer, Kevser Ozdemir, Gulden Ersoz, Ahmet Sahin, Ilhami Celik, Emsal Aydin, Aliye Bastug, Rezan Harman, Hacer Deniz Ozkaya, Emine Parlak, Ilknur Yavuz, Suzan Sacar, Senol Comoglu, Ercan Yenilmez, Fatma Sirmatel, Ilker Inanc Balkan, Yesim Alpay, Mustafa Hatipoglu, Affan Denk, Gunes Senol, Mehmet Bitirgen, Mehmet Faruk Geyik, Rahmet Guner, Ayten Kadanali, Ahmet Karakas, Mustafa Namiduru, Hatice Udurgucu, Rukiye Pinar Boluktas, Ergenekon Karagoz, Necati Ormeci |
Abstract |
The aim of this study was to assess health-related quality of life (HRQOL) among chronic hepatitis B (CHB) patients in Turkey and to study related factors. This multicenter study was carried out between January 01 and April 15, 2015 in Turkey in 57 centers. Adults were enrolled and studied in three groups. Group 1: Inactive HBsAg carriers, Group 2: CHB patients receiving antiviral therapy, Group 3: CHB patients who were neither receiving antiviral therapy nor were inactive HBsAg carriers. Study data was collected by face-to-face interviews using a standardized questionnaire, Short Form-36 (SF-36) and Hepatitis B Quality of Life (HBQOL). Values equivalent to p < 0.05 in analyses were accepted as statistically significant. Four thousand two hundred fifty-seven patients with CHB were included in the study. Two thousand five hundred fifty-nine (60.1 %) of the patients were males. Groups 1, 2 and 3, consisted of 1529 (35.9 %), 1721 (40.4 %) and 1007 (23.7 %) patients, respectively. The highest value of HRQOL was found in inactive HBsAg carriers. We found that total HBQOL score increased when antiviral treatment was used. However, HRQOL of CHB patients varied according to their socio-demographic properties. Regarding total HBQOL score, a higher significant level of HRQOL was determined in inactive HBV patients when matched controls with the associated factors were provided. The HRQOL score of CHB patients was higher than expected and it can be worsen when the disease becomes active. Use of an antiviral therapy can contribute to increasing HRQOL of patients. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 76 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 9 | 12% |
Student > Ph. D. Student | 7 | 9% |
Student > Master | 7 | 9% |
Student > Doctoral Student | 5 | 7% |
Student > Bachelor | 4 | 5% |
Other | 17 | 22% |
Unknown | 27 | 36% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 15 | 20% |
Nursing and Health Professions | 13 | 17% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 5% |
Agricultural and Biological Sciences | 3 | 4% |
Psychology | 3 | 4% |
Other | 8 | 11% |
Unknown | 30 | 39% |