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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Label-assisted mass spectrometry for the acceleration of reaction discovery and optimization
|
|---|---|
| Published in |
Nature Chemistry, March 2013
|
| DOI | 10.1038/nchem.1612 |
| Pubmed ID | |
| Authors |
Jaime R. Cabrera-Pardo, David I. Chai, Song Liu, Milan Mrksich, Sergey A. Kozmin |
| Abstract |
The identification of new reactions expands our knowledge of chemical reactivity and enables new synthetic applications. Accelerating the pace of this discovery process remains challenging. We describe a highly effective and simple platform for screening a large number of potential chemical reactions in order to discover and optimize previously unknown catalytic transformations, thereby revealing new chemical reactivity. Our strategy is based on labelling one of the reactants with a polyaromatic chemical tag, which selectively undergoes a photoionization/desorption process upon laser irradiation, without the assistance of an external matrix, and enables rapid mass spectrometric detection of any products originating from such labelled reactants in complex reaction mixtures without any chromatographic separation. This method was successfully used for high-throughput discovery and subsequent optimization of two previously unknown benzannulation reactions. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | 25% |
| United Kingdom | 1 | 25% |
| Australia | 1 | 25% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 2 | 50% |
| Members of the public | 2 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 3 | 4% |
| United Kingdom | 2 | 3% |
| France | 1 | 1% |
| Unknown | 69 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 23 | 31% |
| Researcher | 16 | 21% |
| Student > Bachelor | 10 | 13% |
| Student > Master | 7 | 9% |
| Professor | 4 | 5% |
| Other | 9 | 12% |
| Unknown | 6 | 8% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 51 | 68% |
| Biochemistry, Genetics and Molecular Biology | 4 | 5% |
| Agricultural and Biological Sciences | 4 | 5% |
| Engineering | 3 | 4% |
| Materials Science | 2 | 3% |
| Other | 5 | 7% |
| Unknown | 6 | 8% |
Attention Score in Context
This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 December 2022.
All research outputs
#1,768,665
of 23,332,901 outputs
Outputs from Nature Chemistry
#1,445
of 3,053 outputs
Outputs of similar age
#14,897
of 201,436 outputs
Outputs of similar age from Nature Chemistry
#22
of 61 outputs
Altmetric has tracked 23,332,901 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,053 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 35.1. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 201,436 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 61 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.