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Ghrelin inhibits LPS-induced release of IL-6 from mouse dopaminergic neurones

Overview of attention for article published in Journal of Neuroinflammation, March 2013
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  • Above-average Attention Score compared to outputs of the same age and source (62nd percentile)

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Title
Ghrelin inhibits LPS-induced release of IL-6 from mouse dopaminergic neurones
Published in
Journal of Neuroinflammation, March 2013
DOI 10.1186/1742-2094-10-40
Pubmed ID
Authors

Amy L Beynon, M Rowan Brown, Rhiannon Wright, Mark I Rees, I Martin Sheldon, Jeffrey S Davies

Abstract

Ghrelin is an orexigenic stomach hormone that acts centrally to increase mid-brain dopamine neurone activity, amplify dopamine signaling and protect against neurotoxin-induced dopamine cell death in the mouse substantia nigra pars compacta (SNpc). In addition, ghrelin inhibits the lipopolysaccharide (LPS)-induced release of pro-inflammatory cytokines from peripheral macrophages, T-cells and from LPS stimulated microglia. Here we sought to determine whether ghrelin attenuates pro-inflammatory cytokine release from dopaminergic neurones.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Brazil 1 2%
Unknown 43 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 31%
Student > Postgraduate 5 11%
Student > Master 5 11%
Researcher 4 9%
Professor > Associate Professor 4 9%
Other 7 16%
Unknown 6 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 22%
Medicine and Dentistry 8 18%
Neuroscience 7 16%
Biochemistry, Genetics and Molecular Biology 4 9%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Other 6 13%
Unknown 8 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 May 2020.
All research outputs
#13,380,993
of 22,703,044 outputs
Outputs from Journal of Neuroinflammation
#1,436
of 2,612 outputs
Outputs of similar age
#105,554
of 197,434 outputs
Outputs of similar age from Journal of Neuroinflammation
#11
of 32 outputs
Altmetric has tracked 22,703,044 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,612 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 197,434 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.