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Paper-Based Microfluidic Surface Acoustic Wave Sample Delivery and Ionization Source for Rapid and Sensitive Ambient Mass Spectrometry

Overview of attention for article published in Analytical Chemistry, April 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (89th percentile)
  • High Attention Score compared to outputs of the same age and source (97th percentile)

Mentioned by

patent
8 patents
wikipedia
3 Wikipedia pages
video
1 YouTube creator

Citations

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112 Dimensions

Readers on

mendeley
156 Mendeley
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Title
Paper-Based Microfluidic Surface Acoustic Wave Sample Delivery and Ionization Source for Rapid and Sensitive Ambient Mass Spectrometry
Published in
Analytical Chemistry, April 2011
DOI 10.1021/ac200380q
Pubmed ID
Authors

Jenny Ho, Ming K. Tan, David B. Go, Leslie Y. Yeo, James R. Friend, Hsueh-Chia Chang

Abstract

A surface acoustic wave-based sample delivery and ionization method that requires minimal to no sample pretreatment and that can operate under ambient conditions is described. This miniaturized technology enables real-time, rapid, and high-throughput analysis of trace compounds in complex mixtures, especially high ionic strength and viscous samples that can be challenging for conventional ionization techniques such as electrospray ionization. This technique takes advantage of high order surface acoustic wave (SAW) vibrations that both manipulate small volumes of liquid mixtures containing trace analyte compounds and seamlessly transfers analytes from the liquid sample into gas phase ions for mass spectrometry (MS) analysis. Drugs in human whole blood and plasma and heavy metals in tap water have been successfully detected at nanomolar concentrations by coupling a SAW atomization and ionization device with an inexpensive, paper-based sample delivery system and mass spectrometer. The miniaturized SAW ionization unit requires only a modest operating power of 3 to 4 W and, therefore, provides a viable and efficient ionization platform for the real-time analysis of a wide range of compounds.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 156 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 3 2%
France 2 1%
Canada 2 1%
United States 2 1%
Australia 1 <1%
China 1 <1%
Italy 1 <1%
Unknown 144 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 39 25%
Researcher 28 18%
Student > Master 17 11%
Student > Doctoral Student 12 8%
Professor 9 6%
Other 30 19%
Unknown 21 13%
Readers by discipline Count As %
Engineering 45 29%
Chemistry 35 22%
Agricultural and Biological Sciences 17 11%
Physics and Astronomy 11 7%
Earth and Planetary Sciences 6 4%
Other 13 8%
Unknown 29 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 October 2023.
All research outputs
#2,404,100
of 22,703,044 outputs
Outputs from Analytical Chemistry
#1,059
of 26,374 outputs
Outputs of similar age
#10,957
of 108,815 outputs
Outputs of similar age from Analytical Chemistry
#3
of 131 outputs
Altmetric has tracked 22,703,044 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 26,374 research outputs from this source. They receive a mean Attention Score of 4.7. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 108,815 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 131 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.