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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Antibody recognition of aberrant glycosylation on the surface of cancer cells
|
|---|---|
| Published in |
Current Opinion in Structural Biology, November 2016
|
| DOI | 10.1016/j.sbi.2016.10.009 |
| Pubmed ID | |
| Authors |
Caroline Soliman, Elizabeth Yuriev, Paul A Ramsland |
| Abstract |
Carbohydrate-binding antibodies and carbohydrate-based vaccines are being actively pursued as targeted immunotherapies for a broad range of cancers. Recognition of tumor-associated carbohydrates (glycans) by antibodies is predominantly towards terminal epitopes on glycoproteins and glycolipids on the surface of cancer cells. Crystallography along with complementary experimental and computational methods have been extensively used to dissect antibody recognition of glycan epitopes commonly found in cancer. We provide an overview of the structural biology of antibody recognition of tumor-associated glycans and propose potential rearrangements of these targets in the membrane that could dictate the complex biological activities of these antibodies against cancer cells. |
X Demographics
The data shown below were collected from the profiles of 16 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Poland | 2 | 13% |
| United Kingdom | 2 | 13% |
| United States | 2 | 13% |
| Spain | 1 | 6% |
| Ghana | 1 | 6% |
| France | 1 | 6% |
| Unknown | 7 | 44% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 10 | 63% |
| Scientists | 5 | 31% |
| Science communicators (journalists, bloggers, editors) | 1 | 6% |
Mendeley readers
The data shown below were compiled from readership statistics for 87 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 2 | 2% |
| Germany | 2 | 2% |
| Unknown | 83 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 25 | 29% |
| Student > Master | 13 | 15% |
| Student > Bachelor | 11 | 13% |
| Researcher | 7 | 8% |
| Student > Doctoral Student | 5 | 6% |
| Other | 12 | 14% |
| Unknown | 14 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 20 | 23% |
| Agricultural and Biological Sciences | 20 | 23% |
| Chemistry | 17 | 20% |
| Immunology and Microbiology | 4 | 5% |
| Computer Science | 3 | 3% |
| Other | 10 | 11% |
| Unknown | 13 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 June 2017.
All research outputs
#4,760,313
of 25,374,917 outputs
Outputs from Current Opinion in Structural Biology
#469
of 2,067 outputs
Outputs of similar age
#72,279
of 317,470 outputs
Outputs of similar age from Current Opinion in Structural Biology
#11
of 39 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,067 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 317,470 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 39 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.