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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Theranostic barcoded nanoparticles for personalized cancer medicine
|
|---|---|
| Published in |
Nature Communications, November 2016
|
| DOI | 10.1038/ncomms13325 |
| Pubmed ID | |
| Authors |
Zvi Yaari, Dana da Silva, Assaf Zinger, Evgeniya Goldman, Ashima Kajal, Rafi Tshuva, Efrat Barak, Nitsan Dahan, Dov Hershkovitz, Mor Goldfeder, Janna Shainsky Roitman, Avi Schroeder |
| Abstract |
Personalized medicine promises to revolutionize cancer therapy by matching the most effective treatment to the individual patient. Using a nanoparticle-based system, we predict the therapeutic potency of anticancer medicines in a personalized manner. We carry out the diagnostic stage through a multidrug screen performed inside the tumour, extracting drug activity information with single cell sensitivity. By using 100 nm liposomes, loaded with various cancer drugs and corresponding synthetic DNA barcodes, we find a correlation between the cell viability and the drug it was exposed to, according to the matching barcodes. Based on this screen, we devise a treatment protocol for mice bearing triple-negative breast-cancer tumours, and its results confirm the diagnostic prediction. We show that the use of nanotechnology in cancer care is effective for generating personalized treatment protocols. |
X Demographics
The data shown below were collected from the profiles of 24 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 21% |
| Spain | 2 | 8% |
| Israel | 2 | 8% |
| France | 2 | 8% |
| Ireland | 1 | 4% |
| Greece | 1 | 4% |
| Switzerland | 1 | 4% |
| Serbia | 1 | 4% |
| Germany | 1 | 4% |
| Other | 0 | 0% |
| Unknown | 8 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 21 | 88% |
| Scientists | 3 | 13% |
Mendeley readers
The data shown below were compiled from readership statistics for 209 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | <1% |
| Turkey | 1 | <1% |
| Australia | 1 | <1% |
| Unknown | 205 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 58 | 28% |
| Researcher | 30 | 14% |
| Student > Master | 25 | 12% |
| Student > Bachelor | 14 | 7% |
| Student > Doctoral Student | 12 | 6% |
| Other | 34 | 16% |
| Unknown | 36 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 32 | 15% |
| Chemistry | 30 | 14% |
| Agricultural and Biological Sciences | 22 | 11% |
| Engineering | 19 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 18 | 9% |
| Other | 42 | 20% |
| Unknown | 46 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 80. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 March 2021.
All research outputs
#545,608
of 25,774,185 outputs
Outputs from Nature Communications
#9,315
of 58,396 outputs
Outputs of similar age
#10,307
of 319,966 outputs
Outputs of similar age from Nature Communications
#206
of 966 outputs
Altmetric has tracked 25,774,185 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 58,396 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 55.4. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 319,966 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 966 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.