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Adhesion G Protein-coupled Receptors

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Cover of 'Adhesion G Protein-coupled Receptors'

Table of Contents

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    Book Overview
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    Chapter 1 Introduction: History of the Adhesion GPCR Field.
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    Chapter 2 Classification, Nomenclature, and Structural Aspects of Adhesion GPCRs.
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    Chapter 3 7TM Domain Structure of Adhesion GPCRs.
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    Chapter 4 Understanding the Structural Basis of Adhesion GPCR Functions.
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    Chapter 5 Control of Adhesion GPCR Function Through Proteolytic Processing.
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    Chapter 6 Tethered Agonism: A Common Activation Mechanism of Adhesion GPCRs.
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    Chapter 7 Versatile Signaling Activity of Adhesion GPCRs.
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    Chapter 8 Adhesion G Protein-coupled Receptors
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    Chapter 9 The Relevance of Genomic Signatures at Adhesion GPCR Loci in Humans.
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    Chapter 10 Adhesion GPCRs as a Putative Class of Metabotropic Mechanosensors.
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    Chapter 11 Adhesion GPCRs Govern Polarity of Epithelia and Cell Migration.
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    Chapter 12 Adhesion GPCRs as Novel Actors in Neural and Glial Cell Functions: From Synaptogenesis to Myelination.
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    Chapter 13 Control of Skeletal Muscle Cell Growth and Size Through Adhesion GPCRs.
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    Chapter 14 Adhesion GPCR Function in Pulmonary Development and Disease.
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    Chapter 15 Adhesion GPCRs as Modulators of Immune Cell Function.
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    Chapter 16 Heart Development, Angiogenesis, and Blood-Brain Barrier Function Is Modulated by Adhesion GPCRs.
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    Chapter 17 Adhesion GPCRs in Tumorigenesis.
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    Chapter 18 Erratum to: 7TM Domain Structure of Adhesion GPCRs
Attention for Chapter 16: Heart Development, Angiogenesis, and Blood-Brain Barrier Function Is Modulated by Adhesion GPCRs.
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Chapter title
Heart Development, Angiogenesis, and Blood-Brain Barrier Function Is Modulated by Adhesion GPCRs.
Chapter number 16
Book title
Adhesion G Protein-coupled Receptors
Published in
Handbook of experimental pharmacology, November 2016
DOI 10.1007/978-3-319-41523-9_16
Pubmed ID
Book ISBNs
978-3-31-941521-5, 978-3-31-941523-9
Authors

Gentian Musa, Felix B. Engel, Colin Niaudet

Editors

Tobias Langenhan, Torsten Schöneberg

Abstract

The cardiovascular system in adult organisms forms a network of interconnected endothelial cells, supported by mural cells and displaying a high degree of hierarchy: arteries emerging from the heart ramify into arterioles and then capillaries, which return to the venous systems through venules and veins. The cardiovascular system allows blood circulation, which in turn is essential for hemostasis through gas diffusion, nutrient distribution, and cell trafficking. In this chapter, we have summarized the current knowledge on how adhesion GPCRs (aGPCRs) impact heart development, followed by their role in modulating vascular angiogenesis.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 12 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 3 25%
Student > Ph. D. Student 3 25%
Student > Master 1 8%
Professor > Associate Professor 1 8%
Student > Postgraduate 1 8%
Other 0 0%
Unknown 3 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 5 42%
Agricultural and Biological Sciences 3 25%
Pharmacology, Toxicology and Pharmaceutical Science 1 8%
Neuroscience 1 8%
Unknown 2 17%