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MicroRNA Profiling

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Cover of 'MicroRNA Profiling'

Table of Contents

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    Book Overview
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    Chapter 1 MiRNA Biogenesis and Regulation of Diseases: An Overview.
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    Chapter 2 Assessment of Basic Biological Functions Exerted by miRNAs.
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    Chapter 3 Extraction of miRNAs from Formalin-Fixed Paraffin-Embedded (FFPE) Tissues.
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    Chapter 4 MicroRNA Profiling
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    Chapter 5 MicroRNA Profiling of Exosomes.
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    Chapter 6 MiRNA Profiling in Human Induced Pluripotent Stem Cells.
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    Chapter 7 MiRNA Expression in Cystic Fibrosis Bronchial Epithelial Cells.
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    Chapter 8 TaqMan Low Density Array: MicroRNA Profiling for Biomarker and Oncosuppressor Discovery.
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    Chapter 9 Detection of MicroRNAs in Brain Slices Using In Situ Hybridization.
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    Chapter 10 Exosomal MicroRNA Discovery in Age-Related Macular Degeneration.
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    Chapter 11 Profiling the MicroRNA Payload of Exosomes Derived from Ex Vivo Primary Colorectal Fibroblasts.
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    Chapter 12 Circulating MicroRNAs in Cancer.
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    Chapter 13 Profiling Circulating miRNAs from the Plasma of Individuals with Metabolic Syndrome.
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    Chapter 14 Manipulating MiRNA Expression to Uncover Hidden Functions.
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    Chapter 15 Analysis of the Distribution Profiles of Circulating MicroRNAs by Asymmetrical Flow Field Flow Fractionation.
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    Chapter 16 MicroRNA Expression Profiling Using Agilent One-Color Microarray.
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    Chapter 17 A Multiplex Ligation Assay for miRNA Copy Number Profiling.
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    Chapter 18 Practical Bioinformatics Analysis of MiRNA Data Using Online Tools.
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    Chapter 19 Visualization and Analysis of MiRNA-Targets Interactions Networks.
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    Chapter 20 Guidelines on Designing MicroRNA Sponges: From Construction to Stable Cell Line.
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    Chapter 21 Customization of Artificial MicroRNA Design.
Attention for Chapter 1: MiRNA Biogenesis and Regulation of Diseases: An Overview.
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Chapter title
MiRNA Biogenesis and Regulation of Diseases: An Overview.
Chapter number 1
Book title
MicroRNA Profiling
Published in
Methods in molecular biology, January 2017
DOI 10.1007/978-1-4939-6524-3_1
Pubmed ID
Book ISBNs
978-1-4939-6522-9, 978-1-4939-6524-3
Authors

Anchal Vishnoi, Sweta Rani

Editors

Sweta Rani

Abstract

MicroRNAs (miRNAs) are small RNA molecules, with their role in gene silencing and translational repression by binding to target mRNAs. Since it was discovered in 1993, miRNA are found in all eukaryotic cells conserved across the species. In recent years, regulation of miRNAs are extensively studied for their role in biological processes as well as in development and progression of various human diseases including retinal disorder, neurodegenerative diseases, cardiovascular disease and cancer. This chapter summarises miRNA biogenesis and explores their potential roles in a variety of diseases. miRNAs holds huge potential for diagnostic and prognostic biomarkers, and as predictors of drug response.

Mendeley readers

The data shown below were compiled from readership statistics for 180 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 180 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 35 19%
Student > Master 24 13%
Student > Ph. D. Student 20 11%
Student > Doctoral Student 14 8%
Researcher 12 7%
Other 17 9%
Unknown 58 32%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 58 32%
Medicine and Dentistry 16 9%
Agricultural and Biological Sciences 11 6%
Immunology and Microbiology 7 4%
Neuroscience 6 3%
Other 18 10%
Unknown 64 36%