Chapter title |
MiRNA Biogenesis and Regulation of Diseases: An Overview.
|
---|---|
Chapter number | 1 |
Book title |
MicroRNA Profiling
|
Published in |
Methods in molecular biology, January 2017
|
DOI | 10.1007/978-1-4939-6524-3_1 |
Pubmed ID | |
Book ISBNs |
978-1-4939-6522-9, 978-1-4939-6524-3
|
Authors |
Anchal Vishnoi, Sweta Rani |
Editors |
Sweta Rani |
Abstract |
MicroRNAs (miRNAs) are small RNA molecules, with their role in gene silencing and translational repression by binding to target mRNAs. Since it was discovered in 1993, miRNA are found in all eukaryotic cells conserved across the species. In recent years, regulation of miRNAs are extensively studied for their role in biological processes as well as in development and progression of various human diseases including retinal disorder, neurodegenerative diseases, cardiovascular disease and cancer. This chapter summarises miRNA biogenesis and explores their potential roles in a variety of diseases. miRNAs holds huge potential for diagnostic and prognostic biomarkers, and as predictors of drug response. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 332 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 53 | 16% |
Student > Master | 35 | 11% |
Student > Ph. D. Student | 31 | 9% |
Researcher | 25 | 8% |
Student > Doctoral Student | 19 | 6% |
Other | 31 | 9% |
Unknown | 138 | 42% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 96 | 29% |
Medicine and Dentistry | 23 | 7% |
Agricultural and Biological Sciences | 16 | 5% |
Immunology and Microbiology | 10 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 6 | 2% |
Other | 33 | 10% |
Unknown | 148 | 45% |