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MicroRNA Profiling

Overview of attention for book
Cover of 'MicroRNA Profiling'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 1 MiRNA Biogenesis and Regulation of Diseases: An Overview.
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    Chapter 2 Assessment of Basic Biological Functions Exerted by miRNAs.
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    Chapter 3 Extraction of miRNAs from Formalin-Fixed Paraffin-Embedded (FFPE) Tissues.
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    Chapter 4 MicroRNA Profiling
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    Chapter 5 MicroRNA Profiling of Exosomes.
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    Chapter 6 MiRNA Profiling in Human Induced Pluripotent Stem Cells.
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    Chapter 7 MiRNA Expression in Cystic Fibrosis Bronchial Epithelial Cells.
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    Chapter 8 TaqMan Low Density Array: MicroRNA Profiling for Biomarker and Oncosuppressor Discovery.
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    Chapter 9 Detection of MicroRNAs in Brain Slices Using In Situ Hybridization.
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    Chapter 10 Exosomal MicroRNA Discovery in Age-Related Macular Degeneration.
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    Chapter 11 Profiling the MicroRNA Payload of Exosomes Derived from Ex Vivo Primary Colorectal Fibroblasts.
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    Chapter 12 Circulating MicroRNAs in Cancer.
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    Chapter 13 Profiling Circulating miRNAs from the Plasma of Individuals with Metabolic Syndrome.
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    Chapter 14 Manipulating MiRNA Expression to Uncover Hidden Functions.
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    Chapter 15 Analysis of the Distribution Profiles of Circulating MicroRNAs by Asymmetrical Flow Field Flow Fractionation.
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    Chapter 16 MicroRNA Expression Profiling Using Agilent One-Color Microarray.
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    Chapter 17 A Multiplex Ligation Assay for miRNA Copy Number Profiling.
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    Chapter 18 Practical Bioinformatics Analysis of MiRNA Data Using Online Tools.
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    Chapter 19 Visualization and Analysis of MiRNA-Targets Interactions Networks.
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    Chapter 20 Guidelines on Designing MicroRNA Sponges: From Construction to Stable Cell Line.
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    Chapter 21 Customization of Artificial MicroRNA Design.
Attention for Chapter 10: Exosomal MicroRNA Discovery in Age-Related Macular Degeneration.
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Chapter title
Exosomal MicroRNA Discovery in Age-Related Macular Degeneration.
Chapter number 10
Book title
MicroRNA Profiling
Published in
Methods in molecular biology, January 2017
DOI 10.1007/978-1-4939-6524-3_10
Pubmed ID
Book ISBNs
978-1-4939-6522-9, 978-1-4939-6524-3
Authors

Hanan Elshelmani, Sweta Rani, Elshelmani, Hanan, Rani, Sweta

Editors

Sweta Rani

Abstract

Age-related macular degeneration (AMD) is a common condition causing progressive visual impairment, leading to irreversible blindness. Existing diagnostic tools for AMD are limited to clinical signs in the macula and the visual assessment of the patient. The presence of circulating microRNAs (miRNAs) in the peripheral circulatory system with potential as diagnostic, prognostic and/or predictive biomarkers has been reported in a number of conditions/diseases. miRNAs are key regulators of several biological processes, and miRNA dysregulation has been linked with numerous diseases, most remarkably cancer. miRNAs have been shown to be involved in AMD pathology and several miRNAs target genes and signaling pathways were identified in relation to AMD pathogenesis. Exosomes are 50-90 nm membrane micro-vesicles (MVs), released by several cell types. Although exosomal functions are not completely understood, there is much evidence to suggest that exosomes play an essential role in cell-cell communication. They may stimulate target cells by transferring different bioactive molecules such as miRNA. Here we discuss methods to isolate exosome using serum specimens from AMD patients and miRNA profiling for the better understanding of the disease.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 20 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 20%
Researcher 2 10%
Student > Bachelor 2 10%
Student > Doctoral Student 2 10%
Unspecified 1 5%
Other 4 20%
Unknown 5 25%
Readers by discipline Count As %
Medicine and Dentistry 8 40%
Biochemistry, Genetics and Molecular Biology 3 15%
Unspecified 1 5%
Business, Management and Accounting 1 5%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Other 1 5%
Unknown 5 25%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 November 2016.
All research outputs
#6,582,788
of 8,642,080 outputs
Outputs from Methods in molecular biology
#3,287
of 6,402 outputs
Outputs of similar age
#166,749
of 239,952 outputs
Outputs of similar age from Methods in molecular biology
#25
of 36 outputs
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