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MicroRNA Profiling

Overview of attention for book
Cover of 'MicroRNA Profiling'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 1 MiRNA Biogenesis and Regulation of Diseases: An Overview.
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    Chapter 2 Assessment of Basic Biological Functions Exerted by miRNAs.
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    Chapter 3 Extraction of miRNAs from Formalin-Fixed Paraffin-Embedded (FFPE) Tissues.
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    Chapter 4 MicroRNA Profiling
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    Chapter 5 MicroRNA Profiling of Exosomes.
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    Chapter 6 MiRNA Profiling in Human Induced Pluripotent Stem Cells.
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    Chapter 7 MiRNA Expression in Cystic Fibrosis Bronchial Epithelial Cells.
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    Chapter 8 TaqMan Low Density Array: MicroRNA Profiling for Biomarker and Oncosuppressor Discovery.
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    Chapter 9 Detection of MicroRNAs in Brain Slices Using In Situ Hybridization.
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    Chapter 10 Exosomal MicroRNA Discovery in Age-Related Macular Degeneration.
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    Chapter 11 Profiling the MicroRNA Payload of Exosomes Derived from Ex Vivo Primary Colorectal Fibroblasts.
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    Chapter 12 Circulating MicroRNAs in Cancer.
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    Chapter 13 Profiling Circulating miRNAs from the Plasma of Individuals with Metabolic Syndrome.
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    Chapter 14 Manipulating MiRNA Expression to Uncover Hidden Functions.
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    Chapter 15 Analysis of the Distribution Profiles of Circulating MicroRNAs by Asymmetrical Flow Field Flow Fractionation.
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    Chapter 16 MicroRNA Expression Profiling Using Agilent One-Color Microarray.
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    Chapter 17 A Multiplex Ligation Assay for miRNA Copy Number Profiling.
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    Chapter 18 Practical Bioinformatics Analysis of MiRNA Data Using Online Tools.
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    Chapter 19 Visualization and Analysis of MiRNA-Targets Interactions Networks.
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    Chapter 20 Guidelines on Designing MicroRNA Sponges: From Construction to Stable Cell Line.
  22. Altmetric Badge
    Chapter 21 Customization of Artificial MicroRNA Design.
Attention for Chapter 12: Circulating MicroRNAs in Cancer.
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (66th percentile)
  • Good Attention Score compared to outputs of the same age and source (76th percentile)

Mentioned by

twitter
5 tweeters

Citations

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4 Dimensions

Readers on

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8 Mendeley
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Chapter title
Circulating MicroRNAs in Cancer.
Chapter number 12
Book title
MicroRNA Profiling
Published in
Methods in molecular biology, January 2017
DOI 10.1007/978-1-4939-6524-3_12
Pubmed ID
Book ISBNs
978-1-4939-6522-9, 978-1-4939-6524-3
Authors

Killian P. O’Brien, Eimear Ramphul, Linda Howard, William M. Gallagher, Carmel Malone, Michael J. Kerin, Róisín M. Dwyer, O'Brien, Killian P, Ramphul, Eimear, Howard, Linda, Gallagher, William M, Malone, Carmel, Kerin, Michael J, Dwyer, Róisín M

Editors

Sweta Rani

Abstract

It is believed that microRNAs have potential as circulating biomarkers of disease; however, successful clinical implementation remains a challenge. This chapter highlights broad variations in approaches to microRNA analysis where whole blood, serum and plasma have each been employed as viable sources. Further discrepancies in approaches are seen in endogenous controls and extraction methods utilized. This has resulted in contradictory publications, even when the same microRNA is targeted in the same disease setting.Analysis of blood samples highlighted the impact of both collection method and storage, on the microRNA profile. Analysis of a panel of microRNAs across whole blood, serum, and plasma originating from the same individual emphasized the impact of starting material on microRNA profile. This is a highly topical field of research with immense potential for translation into the clinical setting. Standardization of sample harvesting, processing and analysis will be key to this translation. Methods of sample harvesting, preservation, and analysis are outlined, with important mitigating factors highlighted.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 3 38%
Student > Bachelor 1 13%
Student > Ph. D. Student 1 13%
Unknown 3 38%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 3 38%
Medicine and Dentistry 2 25%
Agricultural and Biological Sciences 1 13%
Unknown 2 25%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 December 2016.
All research outputs
#2,465,227
of 9,677,238 outputs
Outputs from Methods in molecular biology
#947
of 7,415 outputs
Outputs of similar age
#81,238
of 244,182 outputs
Outputs of similar age from Methods in molecular biology
#13
of 56 outputs
Altmetric has tracked 9,677,238 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 7,415 research outputs from this source. They receive a mean Attention Score of 2.0. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,182 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 56 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.