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Gelsolin activity controls efficient early HIV-1 infection

Overview of attention for article published in Retrovirology: Research & Treatment, January 2013
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Mentioned by

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2 tweeters

Citations

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27 Dimensions

Readers on

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26 Mendeley
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Title
Gelsolin activity controls efficient early HIV-1 infection
Published in
Retrovirology: Research & Treatment, January 2013
DOI 10.1186/1742-4690-10-39
Pubmed ID
Authors

Laura García-Expósito, Serena Ziglio, Jonathan Barroso-González, Laura de Armas-Rillo, María-Soledad Valera, Donato Zipeto, José-David Machado, Agustín Valenzuela-Fernández

Abstract

HIV-1 entry into target lymphocytes requires the activity of actin adaptors that stabilize and reorganize cortical F-actin, like moesin and filamin-A. These alterations are necessary for the redistribution of CD4-CXCR4/CCR5 to one pole of the cell, a process that increases the probability of HIV-1 Envelope (Env)-CD4/co-receptor interactions and that generates the tension at the plasma membrane necessary to potentiate fusion pore formation, thereby favouring early HIV-1 infection. However, it remains unclear whether the dynamic processing of F-actin and the amount of cortical actin available during the initial virus-cell contact are required to such events.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 4%
Unknown 25 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 19%
Researcher 4 15%
Student > Bachelor 3 12%
Professor 3 12%
Other 2 8%
Other 8 31%
Unknown 1 4%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 35%
Biochemistry, Genetics and Molecular Biology 7 27%
Immunology and Microbiology 5 19%
Medicine and Dentistry 3 12%
Philosophy 1 4%
Other 1 4%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 April 2013.
All research outputs
#8,080,389
of 10,677,937 outputs
Outputs from Retrovirology: Research & Treatment
#302
of 453 outputs
Outputs of similar age
#81,954
of 127,942 outputs
Outputs of similar age from Retrovirology: Research & Treatment
#16
of 24 outputs
Altmetric has tracked 10,677,937 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 453 research outputs from this source. They receive a mean Attention Score of 3.9. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 127,942 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.