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Vitamin K prior to preterm birth for preventing neonatal periventricular haemorrhage

Overview of attention for article published in Cochrane database of systematic reviews, January 2000
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Title
Vitamin K prior to preterm birth for preventing neonatal periventricular haemorrhage
Published in
Cochrane database of systematic reviews, January 2000
DOI 10.1002/14651858.cd000229
Pubmed ID
Authors

Crowther, C A, Henderson-Smart, D J, Crowther, Caroline A, Crosby, Danielle D, Henderson-Smart, David J

Abstract

Preterm infants are at risk of periventricular haemorrhage. This can damage the brain and lead to neurodevelopmental abnormalities, including cerebral palsy. It has been suggested that vitamin K might improve coagulation in preterm infants. The objective of this review was to assess the effects of vitamin K administered to women at risk of imminent very preterm birth to prevent periventricular haemorrhage and associated neurological injury in the infant. We searched the Cochrane Pregnancy and Childbirth Group trials register, Cochrane Controlled Trials Register, and bibliographies up to January 1999. Randomised or quasi-randomised trials of vitamin K administered parenterally or orally to women at risk of imminent preterm birth. The primary outcomes were neonatal mortality, neonatal neurological morbidity, as measured by the presence of periventricular haemorrhage (PVH) on ultrasound during the first week of life, and long term neurodevelopment. Secondary outcomes included other neonatal morbidity and any maternal side effects. Eligibility, trial quality assessment and data extraction were done independently by two reviewers. Five trials were included, involving more than 420 women. The trials were of variable quality. Antenatal vitamin K was associated with a non-significant trend to a reduction in all grades of periventricular haemorrhage (relative risk (RR) 0.82, 95% confidence interval (CI) 0.67-1.00) and in severe PVH (grades 3 and 4) (RR 0.75, 95% CI 0.45-1.25) for babies receiving prenatal vitamin K compared with control babies. This trend disappeared when poorer quality trials were excluded. Information on neurodevelopment was given for a small sample of children in one trial and no differences were seen. Vitamin K administered to women prior to very preterm birth does not appear to be able to significantly prevent periventricular haemorrhages in preterm infants.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
South Africa 1 2%
Unknown 53 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 14 25%
Researcher 10 18%
Student > Ph. D. Student 6 11%
Student > Doctoral Student 5 9%
Librarian 4 7%
Other 10 18%
Unknown 6 11%
Readers by discipline Count As %
Medicine and Dentistry 27 49%
Social Sciences 5 9%
Nursing and Health Professions 4 7%
Psychology 4 7%
Business, Management and Accounting 1 2%
Other 5 9%
Unknown 9 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 June 2013.
All research outputs
#7,492,173
of 22,901,818 outputs
Outputs from Cochrane database of systematic reviews
#8,968
of 12,335 outputs
Outputs of similar age
#24,339
of 107,955 outputs
Outputs of similar age from Cochrane database of systematic reviews
#14
of 35 outputs
Altmetric has tracked 22,901,818 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 12,335 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 30.5. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 107,955 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.