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Lung Cancer and Personalized Medicine: Novel Therapies and Clinical Management

Overview of attention for book
Attention for Chapter 11: Lung Cancer and Personalized Medicine: Novel Therapies and Clinical Management
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Chapter title
Lung Cancer and Personalized Medicine: Novel Therapies and Clinical Management
Chapter number 11
Book title
Lung Cancer and Personalized Medicine: Novel Therapies and Clinical Management
Published in
Advances in experimental medicine and biology, December 2015
DOI 10.1007/978-3-319-24932-2_11
Pubmed ID
Book ISBNs
978-3-31-924931-5, 978-3-31-924932-2
Authors

Gadgeel, Shirish M, Shirish M. Gadgeel M.D., Shirish M. Gadgeel

Editors

Aamir Ahmad, Shirish M. Gadgeel

Abstract

Lung cancer remains the most common cause of cancer related deaths in both men and women in the United States and non-small cell lung cancer (NSCLC) accounts for over 85 % of all lung cancers. Survival of these patients has not significantly altered in over 30 years. This chapter initially discusses the clinical presentation of lung cancer patients. Most patients diagnosed with lung cancer due to symptoms have advanced stage cancer. Once diagnosed, lung cancer patients need imaging studies to assess the stage of the disease before decisions regarding therapy are finalized. The most important prognostic factors are stage of the disease and performance status and these factors also determine therapy. The chapter subsequently discusses management of each stage of the disease and the impact of several pathologic, clinical factors in personalizing therapy for each individual patient. Transition from chemotherapy for every patient to a more personalized approach based on histology and molecular markers has occurred in the management of advanced stage NSCLC. It is expected that such a personalized approach will extend to all stages of NSCLC and will likely improve the outcomes of all NSCLC patients.

Mendeley readers

The data shown below were compiled from readership statistics for 105 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Unknown 104 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 30 29%
Student > Master 11 10%
Student > Doctoral Student 9 9%
Student > Ph. D. Student 8 8%
Student > Postgraduate 6 6%
Other 19 18%
Unknown 22 21%
Readers by discipline Count As %
Medicine and Dentistry 28 27%
Nursing and Health Professions 13 12%
Biochemistry, Genetics and Molecular Biology 9 9%
Agricultural and Biological Sciences 7 7%
Pharmacology, Toxicology and Pharmaceutical Science 5 5%
Other 21 20%
Unknown 22 21%