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The IGF1small dog haplotype is derived from Middle Eastern grey wolves

Overview of attention for article published in BMC Biology, February 2010
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4 news outlets
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1 blog
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3 X users
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3 Wikipedia pages

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Title
The IGF1small dog haplotype is derived from Middle Eastern grey wolves
Published in
BMC Biology, February 2010
DOI 10.1186/1741-7007-8-16
Pubmed ID
Authors

Melissa M Gray, Nathan B Sutter, Elaine A Ostrander, Robert K Wayne

Abstract

A selective sweep containing the insulin-like growth factor 1 (IGF1) gene is associated with size variation in domestic dogs. Intron 2 of IGF1 contains a SINE element and single nucleotide polymorphism (SNP) found in all small dog breeds that is almost entirely absent from large breeds. In this study, we surveyed a large sample of grey wolf populations to better understand the ancestral pattern of variation at IGF1 with a particular focus on the distribution of the small dog haplotype and its relationship to the origin of the dog.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 142 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 7 5%
Portugal 1 <1%
Italy 1 <1%
Mexico 1 <1%
Czechia 1 <1%
Spain 1 <1%
Korea, Republic of 1 <1%
Unknown 129 91%

Demographic breakdown

Readers by professional status Count As %
Researcher 35 25%
Student > Ph. D. Student 29 20%
Student > Bachelor 18 13%
Student > Master 15 11%
Professor > Associate Professor 8 6%
Other 24 17%
Unknown 13 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 84 59%
Biochemistry, Genetics and Molecular Biology 11 8%
Arts and Humanities 6 4%
Social Sciences 5 4%
Veterinary Science and Veterinary Medicine 4 3%
Other 17 12%
Unknown 15 11%