Title |
Magnetic core-shell nanoparticles for drug delivery by nebulization
|
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Published in |
Journal of Nanobiotechnology, January 2013
|
DOI | 10.1186/1477-3155-11-1 |
Pubmed ID | |
Authors |
Navin Kumar Verma, Kieran Crosbie-Staunton, Amro Satti, Shane Gallagher, Katie B Ryan, Timothy Doody, Colm McAtamney, Ronan MacLoughlin, Paul Galvin, Conor S Burke, Yuri Volkov, Yurii K Gun’ko |
Abstract |
Aerosolized therapeutics hold great potential for effective treatment of various diseases including lung cancer. In this context, there is an urgent need to develop novel nanocarriers suitable for drug delivery by nebulization. To address this need, we synthesized and characterized a biocompatible drug delivery vehicle following surface coating of Fe3O4 magnetic nanoparticles (MNPs) with a polymer poly(lactic-co-glycolic acid) (PLGA). The polymeric shell of these engineered nanoparticles was loaded with a potential anti-cancer drug quercetin and their suitability for targeting lung cancer cells via nebulization was evaluated. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Iran, Islamic Republic of | 2 | 1% |
Italy | 1 | <1% |
United Kingdom | 1 | <1% |
Malaysia | 1 | <1% |
Saudi Arabia | 1 | <1% |
Ukraine | 1 | <1% |
Spain | 1 | <1% |
United States | 1 | <1% |
Unknown | 186 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 43 | 22% |
Student > Master | 30 | 15% |
Researcher | 25 | 13% |
Student > Bachelor | 12 | 6% |
Student > Doctoral Student | 11 | 6% |
Other | 24 | 12% |
Unknown | 50 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Chemistry | 23 | 12% |
Agricultural and Biological Sciences | 20 | 10% |
Materials Science | 19 | 10% |
Pharmacology, Toxicology and Pharmaceutical Science | 17 | 9% |
Medicine and Dentistry | 13 | 7% |
Other | 44 | 23% |
Unknown | 59 | 30% |