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Synthesis and stability of IR-820 and FITC doped silica nanoparticles

Overview of attention for article published in Journal of Colloid & Interface Science, March 2017
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1 tweeter
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1 Facebook page

Citations

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5 Dimensions

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35 Mendeley
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1 CiteULike
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Title
Synthesis and stability of IR-820 and FITC doped silica nanoparticles
Published in
Journal of Colloid & Interface Science, March 2017
DOI 10.1016/j.jcis.2016.11.055
Pubmed ID
Authors

Atul V. Thorat, Tandra Ghoshal, Lan Chen, Justin D. Holmes, Michael A. Morris

Abstract

Fluorescent silica nanoparticles (NPs) have potential in biomedical applications as diagnostics and traceable drug delivery agents. In this study, we have synthesized fluorescent dye grafted silica NPs in two step process. First, a stable method to synthesize various sizes of silica NPs ranging from 20 to 52, 95, 210 and 410nm have been successfully demonstrated. Secondly, as-synthesized silica NPs are readily grafted with some fluorescent dyes like IR-820 and fluorescein isothiocyanate (FITC) dyes by simple impregnation method. IR-820 and FITC dyes are 'activated' by (3-mercaptopropyl)trimethoxysilane (MPTMS) and (3-aminopropyl)triethoxysilane (APTS) respectively prior to the grafting on silica NPs. UV-vis spectroscopy is used to test the stability of dye grafted silica NPs. The fluorescent dye grafted silica NPs are quite stable in aqueous solution. Also, a new type of dual dye-doped hybrid silica nanoparticles has been developed. The combination of microscopic and spectroscopic techniques shows that the synthesis parameters have significant effects on the particle shape and size and is tuneable from a few nanometers to a few hundred nanometers. The ability to create size controlled nanoparticles with associated (optical) functionality may have significant importance in bio-medical imaging.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 35 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 23%
Researcher 6 17%
Student > Bachelor 3 9%
Student > Postgraduate 3 9%
Student > Master 3 9%
Other 5 14%
Unknown 7 20%
Readers by discipline Count As %
Chemistry 6 17%
Materials Science 5 14%
Engineering 4 11%
Pharmacology, Toxicology and Pharmaceutical Science 3 9%
Chemical Engineering 2 6%
Other 5 14%
Unknown 10 29%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 December 2016.
All research outputs
#13,662,883
of 21,075,379 outputs
Outputs from Journal of Colloid & Interface Science
#3,839
of 4,991 outputs
Outputs of similar age
#237,692
of 420,723 outputs
Outputs of similar age from Journal of Colloid & Interface Science
#11
of 41 outputs
Altmetric has tracked 21,075,379 research outputs across all sources so far. This one is in the 33rd percentile – i.e., 33% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,991 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 420,723 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.