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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Role of astrocytes in manganese mediated neurotoxicity
|
|---|---|
| Published in |
BMC Pharmacology and Toxicology, April 2013
|
| DOI | 10.1186/2050-6511-14-23 |
| Pubmed ID | |
| Authors |
Marta Sidoryk-Wegrzynowicz, Michael Aschner |
| Abstract |
Astrocytes are responsible for numerous aspects of metabolic support, nutrition, control of the ion and neurotransmitter environment in central nervous system (CNS). Failure by astrocytes to support essential neuronal metabolic requirements plays a fundamental role in the pathogenesis of brain injury and the ensuing neuronal death. Astrocyte-neuron interactions play a central role in brain homeostasis, in particular via neurotransmitter recycling functions. Disruption of the glutamine (Gln)/glutamate (Glu) -γ-aminobutyric acid (GABA) cycle (GGC) between astrocytes and neurons contributes to changes in Glu-ergic and/or GABA-ergic transmission, and is associated with several neuropathological conditions, including manganese (Mn) toxicity. In this review, we discuss recent advances in support of the important roles for astrocytes in normal as well as neuropathological conditions primarily those caused by exposure to Mn. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 40% |
| India | 1 | 20% |
| Unknown | 2 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 80% |
| Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 87 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Colombia | 2 | 2% |
| United States | 2 | 2% |
| France | 1 | 1% |
| United Kingdom | 1 | 1% |
| Brazil | 1 | 1% |
| Slovenia | 1 | 1% |
| Poland | 1 | 1% |
| Unknown | 78 | 90% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 20 | 23% |
| Student > Master | 13 | 15% |
| Researcher | 11 | 13% |
| Professor > Associate Professor | 8 | 9% |
| Student > Bachelor | 4 | 5% |
| Other | 15 | 17% |
| Unknown | 16 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 19 | 22% |
| Neuroscience | 15 | 17% |
| Medicine and Dentistry | 11 | 13% |
| Biochemistry, Genetics and Molecular Biology | 7 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 7% |
| Other | 9 | 10% |
| Unknown | 20 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 October 2018.
All research outputs
#3,090,400
of 23,881,329 outputs
Outputs from BMC Pharmacology and Toxicology
#55
of 450 outputs
Outputs of similar age
#25,976
of 199,670 outputs
Outputs of similar age from BMC Pharmacology and Toxicology
#2
of 10 outputs
Altmetric has tracked 23,881,329 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 450 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 199,670 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 8 of them.