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The Lnk/SH2B adaptor provides a fail-safe mechanism to establish the Insulin receptor-Chico interaction

Overview of attention for article published in Cell Communication and Signaling, April 2013
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Title
The Lnk/SH2B adaptor provides a fail-safe mechanism to establish the Insulin receptor-Chico interaction
Published in
Cell Communication and Signaling, April 2013
DOI 10.1186/1478-811x-11-26
Pubmed ID
Authors

Isabel Almudi, Ingrid Poernbacher, Ernst Hafen, Hugo Stocker

Abstract

Insulin/insulin-like growth factor signalling (IIS) has been described as one of the major pathways involved in growth control and homeostasis in multicellular organisms. Whereas its core components are well established, less is known about the molecular functions of IIS regulators. The adaptor molecule Lnk/SH2B has been implicated in IIS but the mechanism by which it promotes IIS activity has remained enigmatic.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
United States 1 3%
Unknown 36 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 34%
Researcher 11 29%
Student > Bachelor 4 11%
Professor 2 5%
Professor > Associate Professor 2 5%
Other 2 5%
Unknown 4 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 37%
Biochemistry, Genetics and Molecular Biology 13 34%
Medicine and Dentistry 2 5%
Nursing and Health Professions 1 3%
Physics and Astronomy 1 3%
Other 3 8%
Unknown 4 11%