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In total, 40.4 % of the analyzed #APIs and 29.6 % of the #API impurities are potential #NitrosaminePrecursors. #NDSRIs #NDMA #NDEA #CarcinogenicChemicals
In total, 40.4 % of the analyzed #APIs and 29.6 % of the #API impurities are potential #NitrosaminePrecursors. #NDSRIs #NDMA #NDEA #CarcinogenicChemicals
This article reports the outcome of an in silico analysis of more than 12,000 #smallmolecule drugs and drug impurities, identifying the nitrosatable structures, assessing their potential to form #nitrosamines under relevant conditions. https://t.co/T3BZx7y