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Proposed new mechanism for food and exercise induced anaphylaxis based on case studies

Overview of attention for article published in Allergy, Asthma & Clinical Immunology, March 2013
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  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (76th percentile)

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9 X users
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1 Google+ user

Citations

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34 Mendeley
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Title
Proposed new mechanism for food and exercise induced anaphylaxis based on case studies
Published in
Allergy, Asthma & Clinical Immunology, March 2013
DOI 10.1186/1710-1492-9-11
Pubmed ID
Authors

Jennifer Yan Fei Chen, Jaclyn Quirt, Kihyuk Jason Lee

Abstract

We present two cases of food and exercise-induced anaphylaxis (FEIA) in patients with a diagnosis of oral allergy syndrome (OAS) to the implicated foods. Patient A had FEIA attributed to fresh coriander and tomato and Patient B to fresh celery. These food allergens have been implicated in OAS and have structural antigenic similarity to that of birch and/or grass. Both patients' allergies were confirmed by fresh skin prick tests. In both cases, strenuous exercise was antecedent to the systemic anaphylaxis reaction and subsequent ingestion without exercise produced only local symptoms of perioral pruritus. We review the current proposed mechanisms for food and exercise induced anaphylaxis to oral allergens and propose a novel and more biologically plausible mechanism. We hypothesize that the inhibitory effects of exercise on gastric acid secretion decreases the digestion of oral allergens and preserves structural integrity, thereby allowing continued systemic absorption of the allergen whether it be profilins, lipid transfer proteins, or other antigenic determinants.

X Demographics

X Demographics

The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 34 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 18%
Professor > Associate Professor 3 9%
Student > Ph. D. Student 3 9%
Student > Bachelor 3 9%
Lecturer 2 6%
Other 7 21%
Unknown 10 29%
Readers by discipline Count As %
Medicine and Dentistry 13 38%
Agricultural and Biological Sciences 4 12%
Immunology and Microbiology 2 6%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Unspecified 1 3%
Other 3 9%
Unknown 10 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 September 2022.
All research outputs
#6,237,961
of 25,373,627 outputs
Outputs from Allergy, Asthma & Clinical Immunology
#336
of 924 outputs
Outputs of similar age
#49,465
of 210,236 outputs
Outputs of similar age from Allergy, Asthma & Clinical Immunology
#6
of 8 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 924 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.8. This one has gotten more attention than average, scoring higher than 63% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,236 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.