↓ Skip to main content

Schizophrenia genomics and proteomics: are we any closer to biomarker discovery?

Overview of attention for article published in Behavioral and Brain Functions, January 2009
Altmetric Badge

Mentioned by

facebook
2 Facebook pages

Citations

dimensions_citation
26 Dimensions

Readers on

mendeley
81 Mendeley
citeulike
2 CiteULike
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Schizophrenia genomics and proteomics: are we any closer to biomarker discovery?
Published in
Behavioral and Brain Functions, January 2009
DOI 10.1186/1744-9081-5-2
Pubmed ID
Abstract

The field of proteomics has made leaps and bounds in the last 10 years particularly in the fields of oncology and cardiovascular medicine. In comparison, neuroproteomics is still playing catch up mainly due to the relative complexity of neurological disorders. Schizophrenia is one such disorder, believed to be the results of multiple factors both genetic and environmental. Affecting over 2 million people in the US alone, it has become a major clinical and public health concern worldwide. This paper gives an update of schizophrenia biomarker research as reviewed by Lakhan in 2006 and gives us a rundown of the progress made during the last two years. Several studies demonstrate the potential of cerebrospinal fluid as a source of neuro-specific biomarkers. Genetic association studies are making headway in identifying candidate genes for schizophrenia. In addition, metabonomics, bioinformatics, and neuroimaging techniques are aiming to complete the picture by filling in knowledge gaps. International cooperation in the form of genomics and protein databases and brain banks is facilitating research efforts. While none of the recent developments described here in qualifies as biomarker discovery, many are likely to be stepping stones towards that goal.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 2 2%
Cuba 1 1%
United Kingdom 1 1%
Russia 1 1%
Japan 1 1%
Unknown 75 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 20 25%
Student > Ph. D. Student 18 22%
Student > Bachelor 10 12%
Student > Master 8 10%
Student > Doctoral Student 6 7%
Other 8 10%
Unknown 11 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 25 31%
Medicine and Dentistry 15 19%
Neuroscience 11 14%
Psychology 6 7%
Biochemistry, Genetics and Molecular Biology 5 6%
Other 6 7%
Unknown 13 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 January 2014.
All research outputs
#18,337,420
of 22,708,120 outputs
Outputs from Behavioral and Brain Functions
#288
of 391 outputs
Outputs of similar age
#157,846
of 169,311 outputs
Outputs of similar age from Behavioral and Brain Functions
#14
of 19 outputs
Altmetric has tracked 22,708,120 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 391 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.9. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 169,311 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 3rd percentile – i.e., 3% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one is in the 5th percentile – i.e., 5% of its contemporaries scored the same or lower than it.