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Genome-wide promoter methylation profile of human testis and epididymis: identified from cell-free seminal DNA

Overview of attention for article published in BMC Genomics, April 2013
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Title
Genome-wide promoter methylation profile of human testis and epididymis: identified from cell-free seminal DNA
Published in
BMC Genomics, April 2013
DOI 10.1186/1471-2164-14-288
Pubmed ID
Authors

Chunlin Wu, Xiaofang Ding, Honggang Li, Changhong Zhu, Chengliang Xiong

Abstract

DNA methylation analysis is useful for investigation of male fertility in mammals, whereas the reliance on tissues limits the research on human. We have previously found the presence of high concentration of cell-free seminal DNA (cfsDNA) in human semen. We proposed that some testis and epididymis-specific methylated promoters could be detected in human cfsDNA, and thus hold promise as noninvasive epigenetic biomarkers for male infertility, of which most cases are caused by defects in testicular sperm production or epididymal sperm maturation.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
China 1 2%
Unknown 47 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 17%
Student > Master 7 15%
Student > Doctoral Student 6 13%
Student > Ph. D. Student 5 10%
Other 4 8%
Other 6 13%
Unknown 12 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 10 21%
Medicine and Dentistry 9 19%
Agricultural and Biological Sciences 6 13%
Veterinary Science and Veterinary Medicine 2 4%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 4 8%
Unknown 16 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 April 2013.
All research outputs
#18,337,420
of 22,708,120 outputs
Outputs from BMC Genomics
#8,153
of 10,624 outputs
Outputs of similar age
#145,089
of 193,061 outputs
Outputs of similar age from BMC Genomics
#97
of 123 outputs
Altmetric has tracked 22,708,120 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 10,624 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 12th percentile – i.e., 12% of its peers scored the same or lower than it.
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We're also able to compare this research output to 123 others from the same source and published within six weeks on either side of this one. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.